Sarizotan 2 HCl salt
- CAS No.
- 177976-12-4
- Chemical Name:
- Sarizotan 2 HCl salt
- Synonyms
- Sarizotan 2HCl;Sarizotan DiHCl;Sarizotan 2 HCl salt
- CBNumber:
- CB53339913
- Molecular Formula:
- C22H22ClFN2O
- Molecular Weight:
- 384.88
- MDL Number:
- MOL File:
- 177976-12-4.mol
- MSDS File:
- SDS
| Melting point | 234-235° |
|---|---|
| alpha | 20 -65° (c = 1 in methanol) |
| FDA UNII | 4D56ANR2VD |
Sarizotan 2 HCl salt price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1224951 | Sarizotan dihydrochloride | 177976-12-4 | 1mg | $388 | 2026-06-04 | Buy |
| ChemScene | CS-1224951 | Sarizotan dihydrochloride | 177976-12-4 | 5mg | $968 | 2026-06-04 | Buy |
| ChemScene | CS-1224951 | Sarizotan dihydrochloride | 177976-12-4 | 10mg | $1415 | 2026-06-04 | Buy |
| Biorbyt Ltd | orb2281177 | Sarizotan 2HCl 98.83% | 177976-12-4 | 1mg | $160 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb2281177 | Sarizotan 2HCl 98.83% | 177976-12-4 | 2mg | $220 | 2026-05-06 | Buy |
Sarizotan 2 HCl salt Chemical Properties, Uses, Production
Uses
Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively[1].
IC 50
5-HT1A Receptor: 0.1 nM (IC50); Human D3 Receptor: 6.8 nM (IC50); 5-HT2A Receptor: 587 nM (IC50); 5-HT2B Receptor: 108 nM (IC50); 5-HT5A Receptor: 313 nM (IC50); Human 5-HT6 Receptor: 3300 nM (IC50); Human 5-HT7 Receptor: 10 nM (IC50)
References
[1] G D Bartoszyk, et al. Sarizotan, a Serotonin 5-HT1A Receptor Agonist and Dopamine Receptor Ligand. J Neural Transm (Vienna). 2004 Feb;111(2):113-26. DOI:10.1007/s00702-003-0094-7
[2] C Marin, et al. Local Administration of Sarizotan Into the Subthalamic Nucleus Attenuates Levodopa-Induced Dyskinesias in 6-OHDA-lesioned Rats. Psychopharmacology (Berl). 2009 Jun;204(2):241-50. DOI:10.1007/s00213-008-1452-9
Sarizotan 2 HCl salt Preparation Products And Raw materials
Raw materials
Preparation Products
Sarizotan 2 HCl salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 18100677375 | sales@szzxbio.com | China | 1129 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
| TLC Pharmaceutical Standards Ltd. | 18012923235 | chinasales04@tlcstandards.com.cn | China | 8143 | 58 |
View Latest Price from Sarizotan 2 HCl salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-31 | Sarizotan 2HCl
177976-12-4
|
$117.00-415.00 | 99.82% | 10g | TargetMol Chemicals Inc. |
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- Sarizotan 2HCl
177976-12-4
- $117.00-415.00
- 99.82%
- TargetMol Chemicals Inc.




