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Sarizotan 2 HCl salt

CAS No.
177976-12-4
Chemical Name:
Sarizotan 2 HCl salt
Synonyms
Sarizotan 2HCl;Sarizotan DiHCl;Sarizotan 2 HCl salt
CBNumber:
CB53339913
Molecular Formula:
C22H22ClFN2O
Molecular Weight:
384.88
MDL Number:
MOL File:
177976-12-4.mol
MSDS File:
SDS
Last updated:2026-08-02 18:55:13

Sarizotan 2 HCl salt Properties

Melting point 234-235°
alpha 20 -65° (c = 1 in methanol)
FDA UNII 4D56ANR2VD

Sarizotan 2 HCl salt price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1224951 Sarizotan dihydrochloride 177976-12-4 1mg $388 2026-06-04 Buy
ChemScene CS-1224951 Sarizotan dihydrochloride 177976-12-4 5mg $968 2026-06-04 Buy
ChemScene CS-1224951 Sarizotan dihydrochloride 177976-12-4 10mg $1415 2026-06-04 Buy
Biorbyt Ltd orb2281177 Sarizotan 2HCl 98.83% 177976-12-4 1mg $160 2026-05-06 Buy
Biorbyt Ltd orb2281177 Sarizotan 2HCl 98.83% 177976-12-4 2mg $220 2026-05-06 Buy
Product number Packaging Price Buy
CS-1224951 1mg $388 Buy
CS-1224951 5mg $968 Buy
CS-1224951 10mg $1415 Buy
orb2281177 1mg $160 Buy
orb2281177 2mg $220 Buy

Sarizotan 2 HCl salt Chemical Properties, Uses, Production

Uses

Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively[1].

IC 50

5-HT1A Receptor: 0.1 nM (IC50); Human D3 Receptor: 6.8 nM (IC50); 5-HT2A Receptor: 587 nM (IC50); 5-HT2B Receptor: 108 nM (IC50); 5-HT5A Receptor: 313 nM (IC50); Human 5-HT6 Receptor: 3300 nM (IC50); Human 5-HT7 Receptor: 10 nM (IC50)

References

[1] G D Bartoszyk, et al. Sarizotan, a Serotonin 5-HT1A Receptor Agonist and Dopamine Receptor Ligand. J Neural Transm (Vienna). 2004 Feb;111(2):113-26. DOI:10.1007/s00702-003-0094-7
[2] C Marin, et al. Local Administration of Sarizotan Into the Subthalamic Nucleus Attenuates Levodopa-Induced Dyskinesias in 6-OHDA-lesioned Rats. Psychopharmacology (Berl). 2009 Jun;204(2):241-50. DOI:10.1007/s00213-008-1452-9

Sarizotan 2 HCl salt Preparation Products And Raw materials

Raw materials

Preparation Products

Sarizotan 2 HCl salt Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 18100677375 sales@szzxbio.com China 1129 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
TLC Pharmaceutical Standards Ltd. 18012923235 chinasales04@tlcstandards.com.cn China 8143 58

View Latest Price from Sarizotan 2 HCl salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sarizotan 2HCl pictures 2026-07-31 Sarizotan 2HCl
177976-12-4
$117.00-415.00 99.82% 10g TargetMol Chemicals Inc.
  • Sarizotan 2HCl pictures
  • Sarizotan 2HCl
    177976-12-4
  • $117.00-415.00
  • 99.82%
  • TargetMol Chemicals Inc.

Sarizotan 2 HCl salt Spectrum

Sarizotan 2 HCl salt Sarizotan 2HCl Sarizotan DiHCl 177976-12-4