ChemicalBook >> CAS DataBase List >>Sarolaner
Sarolaner
- CAS No.
- 1398609-39-6
- Chemical Name:
- Sarolaner
- Synonyms
- Saiolana;Saoranna;PF6450567;Sarolaner;Sharolana;Shalalana;PF 6450567;PF 6450567;PF6450567;Sarolaner(PF-6450567);Sarolaner, 10 mM in DMSO
- CBNumber:
- CB53344764
- Molecular Formula:
- C23H18Cl2F4N2O5S
- Molecular Weight:
- 581.36
- MDL Number:
- MFCD28963963
- MOL File:
- 1398609-39-6.mol
- MSDS File:
- SDS
Last updated:2026-05-28 05:10:13
| Boiling point | 722.7±70.0 °C(Predicted) |
|---|---|
| Density | 1.65±0.1 g/cm3(Predicted) |
| storage temp. | Store at 4°C, sealed storage, away from moisture |
| solubility | DMF: Slightly soluble; DMSO: Slightly soluble; Ethanol: Slightly soluble |
| form | A solid |
| pka | -0.93±0.20(Predicted) |
| color | White to off-white |
| InChIKey | FLEFKKUZMDEUIP-QFIPXVFZSA-N |
| SMILES | C(=O)(N1CC2(C3=C(C=C(C4C[C@](C5=CC(Cl)=C(F)C(Cl)=C5)(C(F)(F)F)ON=4)C=C3)CO2)C1)CS(C)(=O)=O |
| FDA UNII | DM113FTW7F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H400-H302-H410 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P273-P391-P501-P273-P391-P501 | |||||||||
| NFPA 704 |
|
Sarolaner price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37321 | Sarolaner ≥98% | 1398609-39-6 | 5mg | $146 | 2026-04-30 | Buy |
| Cayman Chemical | 37321 | Sarolaner ≥98% | 1398609-39-6 | 10mg | $275 | 2026-04-30 | Buy |
| Cayman Chemical | 37321 | Sarolaner ≥98% | 1398609-39-6 | 25mg | $580 | 2026-04-30 | Buy |
| TRC | TRC-S141670-5MG | Sarolaner | 1398609-39-6 | 5mg | $272 | 2026-06-03 | Buy |
| TRC | TRC-S141670-1MG | Sarolaner | 1398609-39-6 | 1mg | $113 | 2026-06-03 | Buy |
Sarolaner Chemical Properties, Uses, Production
Uses
Sarolaner is used in the making of formulations for the control of ticks in cats, and flea infestations in dogs. A parasiiticide.
in vivo
Sarolaner (2.5 mg/kg; p.o. once) shows 100% efficacious against R. sanguineus and D. reticulatus[1]. Sarolaner (1.25- 5 mg/kg; p.o. once) effectively against I. ricinus[1].
| Animal Model: | Dog infested with R. sanguineus and D. reticulatus[1] |
| Dosage: | 2.5 mg/kg |
| Administration: | Oral gavage; 2.5 mg/kg once |
| Result: | Exibited 100% efficacy against R. sanguineus at 48 hours after treatment and also exhibited 98.0% efficacy againstD. reticulatus. |
| Animal Model: | Dog infested with I. ricinus[1] |
| Dosage: | 1.25, 2.5 and 5 mg/kg |
| Administration: | Oral gavage; 1.25, 2.5 and 5 mg/kg once |
| Result: | Exibited 100% efficacy against I. ricinus at all doses until 7 days, and provided over 99.3% reduction against subsequent re-infestations until 57 days at dose of 5.0 and 2.5 mg/kg. |
Synthesis of Sarolaner from Methanesulfonylacetic acid and Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-
Sarolaner Preparation Products And Raw materials
Global Suppliers ( 121)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Madision Biomedical Co., Ltd. | 028-87439248 19150327610;15114076748 | 553691721@qq.com | China | 64 | 58 |
| CHENGHUI PHARMACEUTICAL GROUP LTD | 053158897070 15550412551 | market@jnchsd.com | China | 241 | 58 |
| Jinan Hongkangda Chemical Co., Ltd | 0531-88901705 18753193522 | 810353473@qq.com | China | 156 | 58 |
| Shandong Yuhe Pharmaceutical Technology Co., LTD | 15263077727 | 1436425847@qq.com | China | 296 | 58 |
| Sichuan Qingmu Pharmaceutical Co., Ltd. | 02887827187 | sales@eastonpharma.cn | China | 58 | 60 |
| Hubei Weideli Chemical Reagent Co., Ltd. | 027-83984790 17720532645 | t17720532645@163.com | China | 964 | 58 |
| Jinan Chenghui Shuangda biological Co., LTD | 053158897070 15550412551 | market@jnchsd.com | China | 224 | 62 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4860 | 55 | |
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 7580 | 55 |
View Latest Price from Sarolaner manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-21 | Sarolaner
1398609-39-6
|
$300.00-14500.00 | 1g | 99% | 1000kg | Hebei Dangtong Import and export Co LTD | |
 |
2026-06-30 | Sarolaner
1398609-39-6
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-03-27 | Sarolaner
1398609-39-6
|
1g | 98% HPLC | 1kg | shandong perfect biotechnology co.ltd |
1398609-39-6 (Sarolaner) Related Search:
Sarolaner
1-[6-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]spiro[1H-2-benzofuran-3,3'-azetidine]-1'-yl]-2-methylsulfonylethanone
PF 6450567;PF6450567
PF6450567
PF 6450567
Sarolaner(PF-6450567)
(S)-1-(5'-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone
Ethanone, 1-[5'-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-yl]-2-(methylsulfonyl)-
dog,Sarolaner,Parasite,PF 6450567,flea,Inhibitor,oral,inhibit,isoxazoline,tick,PF6450567
(S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one
Sarolaner, 10 mM in DMSO
Sarolaner (Synonyms: PF-6450567)
Saiolana
Saoranna
Sharolana
(S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one
Sarolaner 100 μg/mL in Acetonitrile
Shalalana
1398609-39-6
C23H18Cl2F4N2O5S
