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11-Keto fluprostenol

11-Keto fluprostenol Structure
11-Keto fluprostenol structure
CAS No.
62145-07-7
Chemical Name:
11-Keto fluprostenol
Synonyms
11-Keto fluprostenol;Travoprost Impurity 22;FLUPROSTENOL PROSTAGLANDIN D2;Travoprost Impurity 17（11-keto Fluprostenol）;11-OXO-9ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-3-oxocyclopentyl]-, (5Z)-
CBNumber:
CB5334872
Molecular Formula:
C23H27F3O6
Molecular Weight:
456.45
MDL Number:
MFCD05863541
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:53:29
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11-Keto fluprostenol Properties

Boiling point 627.3±55.0 °C(Predicted)
Density 1.331±0.06 g/cm3(Predicted)
solubility PBS (7.2): 29 mg/ml
pka 4.76±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H225-H319-H360-H336
Precautionary statements  P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
2 0

11-Keto fluprostenol price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 62145-07-7 1mg $80 2026-04-30 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 62145-07-7 5mg $351 2026-04-30 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 62145-07-7 10mg $622 2026-04-30 Buy
ChemScene CS-0108234 11-keto Fluprostenol 62145-07-7 1mg $171 2026-06-04 Buy
ChemScene CS-0108234 11-keto Fluprostenol 62145-07-7 5mg $760 2026-06-04 Buy
Product number Packaging Price Buy
16783 1mg $80 Buy
16783 5mg $351 Buy
16783 10mg $622 Buy
CS-0108234 1mg $171 Buy
CS-0108234 5mg $760 Buy

11-Keto fluprostenol Chemical Properties,Uses,Production

Description

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor.1 Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.2

Uses

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.

Definition

ChEBI: 11-keto Fluprostenol is a prostanoid.

References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α Nature 250(464),330-331(1974).
2. Monneret, G., Cossette, C., Gravel, S., et al. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils J. Pharmacol. Exp. Ther. 304(1),349-355(2003).

11-Keto fluprostenol Preparation Products And Raw materials

Raw materials

Preparation Products

11-Keto fluprostenol Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679; 13502246435 3008233746@qq.com China 9968 12
Standardpharm Co. Ltd. 86-714-3992388 overseasales1@yongstandards.com United States 14320 58
Jinan blalong chemical co. LTD 2710913286@qq.com 1513643261@qq.com China 14227 58
Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 sales@dmstandards.com China 10922 58
Scinova Biotech(Guangzhou) Co., Ltd. 13268215580 scinova_sales@163.com China 7011 58
Supplier Advantage
Quality Control Solutions Ltd. 56
BOC Sciences 65
Hubei Yangxin Medical Technology Co., Ltd. 55
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 12
Standardpharm Co. Ltd. 58
Jinan blalong chemical co. LTD 58
Guangzhou Juntang Technology Co., Ltd 58
Scinova Biotech(Guangzhou) Co., Ltd. 58

62145-07-7(11-Keto fluprostenol)Related Search:

Tafluprost (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Fluprostenol 9-Keto fluprostenol 9-keto Fluprostenol isopropyl ester
15-Keto Travoprost

1of2

FLUPROSTENOL PROSTAGLANDIN D2 11-OXO-9ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Travoprost Impurity 17（11-keto Fluprostenol） Travoprost Impurity 22 5-Heptenoic acid, 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-3-oxocyclopentyl]-, (5Z)- 11-Keto fluprostenol 62145-07-7