ChemicalBook >> CAS DataBase List >>PF-06726304
PF-06726304
- CAS No.
- 1616287-82-1
- Chemical Name:
- PF-06726304
- Synonyms
- PF-6726304;PF-06726304;PF-06726304, 10 mM in DMSO;antitumor,H3K27me3,PF06726304,Karpas-422,EZH2,PF 06726304,Histone Methyltransferase,inhibit,Inhibitor,PF-06726304,Y641N;5,8-dichloro-2-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7-(3,5-dimethylisoxazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one,;1(2H)-Isoquinolinone, 5,8-dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-;5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
- CBNumber:
- CB53353528
- Molecular Formula:
- C22H21Cl2N3O3
- Molecular Weight:
- 446.33
- MDL Number:
- MFCD31563584
- MOL File:
- 1616287-82-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-11 19:39:08
| Boiling point | 686.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.333±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO : ≥ 15 mg/mL (33.61 mM) |
| form | powder |
| pka | 11.76±0.10(Predicted) |
| color | white to beige |
| SMILES | CC(O)=O.CC(ON=C1C)=C1C2=CC(Cl)=C(CCN(CC3=C(C)C=C(C)NC3=O)C4=O)C4=C2Cl |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
PF-06726304 price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PZ0346 | PF-06726304 acetate ≥98% (HPLC) | 1616287-82-1 | 5mg | $125 | 2026-04-30 | Buy |
| Cayman Chemical | 44260 | PF-06726304 ≥98% | 1616287-82-1 | 1mg | $39 | 2026-04-30 | Buy |
| Cayman Chemical | 44260 | PF-06726304 ≥98% | 1616287-82-1 | 5mg | $97 | 2026-04-30 | Buy |
| Cayman Chemical | 44260 | PF-06726304 ≥98% | 1616287-82-1 | 10mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 44260 | PF-06726304 ≥98% | 1616287-82-1 | 25mg | $385 | 2026-04-30 | Buy |
PF-06726304 Chemical Properties, Uses, Production
Biochem/physiol Actions
PF-06726304 is a selective inhibitor of Histone-lysine N-methyltransferase EZH2 (enhancer of Zeste homolog 2), which catalyzes trimethylation of histone H3 lysine 27 (H3K27) and is amplified and/or overexpressed in several human cancers including breast, prostate and lymphoma. PF-06726304 is a novel structural class of EZH2 inhibitor.
PF-06726304 Preparation Products And Raw materials
Raw materials
Preparation Products
PF-06726304 Suppliers
Global Suppliers ( 55)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Sichuan Yuehe Bio-Pharmaceutical Co.,Ltd | 028-82729560 17365561851 | tangzhichen@yuehepharm.com | China | 215 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4688 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
View Latest Price from PF-06726304 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | PF-06726304
1616287-82-1
|
$33.00-74.00 | 99.51% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-11 | PF-06726304
1616287-82-1
|
$33.00-74.00 | 99.51% | 10g | TargetMol Chemicals Inc. |
-
- PF-06726304
1616287-82-1
- $33.00-74.00
- 99.51%
- TargetMol Chemicals Inc.
-
- PF-06726304
1616287-82-1
- $33.00-74.00
- 99.51%
- TargetMol Chemicals Inc.
PF-06726304
5,8-dichloro-2-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7-(3,5-dimethylisoxazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one,
5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
PF-6726304
1(2H)-Isoquinolinone, 5,8-dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-
antitumor,H3K27me3,PF06726304,Karpas-422,EZH2,PF 06726304,Histone Methyltransferase,inhibit,Inhibitor,PF-06726304,Y641N
PF-06726304, 10 mM in DMSO
1616287-82-1
