| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
PF-06726304 manufacturers
- PF-06726304
-
- $33.00
-
2026-05-11
- CAS:1616287-82-1
- Purity: 99.51%
- Supply Ability: 10g
- PF-06726304
-
- $33.00
-
2026-05-11
- CAS:1616287-82-1
- Purity: 99.51%
- Supply Ability: 10g
|
| | PF-06726304 Basic information |
| Product Name: | PF-06726304 | | Synonyms: | PF-06726304;5,8-dichloro-2-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7-(3,5-dimethylisoxazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one,;5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one;PF-6726304;1(2H)-Isoquinolinone, 5,8-dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-;antitumor,H3K27me3,PF06726304,Karpas-422,EZH2,PF 06726304,Histone Methyltransferase,inhibit,Inhibitor,PF-06726304,Y641N;PF-06726304, 10 mM in DMSO | | CAS: | 1616287-82-1 | | MF: | C22H21Cl2N3O3 | | MW: | 446.33 | | EINECS: | | | Product Categories: | | | Mol File: | 1616287-82-1.mol |  |
| | PF-06726304 Chemical Properties |
| Boiling point | 686.8±55.0 °C(Predicted) | | density | 1.333±0.06 g/cm3(Predicted) | | storage temp. | room temp | | solubility | DMSO : ≥ 15 mg/mL (33.61 mM) | | form | powder | | pka | 11.76±0.10(Predicted) | | color | white to beige | | SMILES | CC(O)=O.CC(ON=C1C)=C1C2=CC(Cl)=C(CCN(CC3=C(C)C=C(C)NC3=O)C4=O)C4=C2Cl |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | PF-06726304 Usage And Synthesis |
| Biochem/physiol Actions | PF-06726304 is a selective inhibitor of Histone-lysine N-methyltransferase EZH2 (enhancer of Zeste homolog 2), which catalyzes trimethylation of histone H3 lysine 27 (H3K27) and is amplified and/or overexpressed in several human cancers including breast, prostate and lymphoma. PF-06726304 is a novel structural class of EZH2 inhibitor. |
| | PF-06726304 Preparation Products And Raw materials |
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