Fmoc-NH-PEG12-CH2CH2COOH
- CAS No.
- 1952360-91-6
- Chemical Name:
- Fmoc-NH-PEG12-CH2CH2COOH
- Synonyms
- FMoc-NH-PEG12-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oic Acid;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;FmocHN-PEG12-PA;Fmoc-nh-peg(16)-cooh;Fmoc-N-amido-PEG12-PA;Fmoc-nh-peg12-C2-cooh;Carboxy-PEG12-(Fmoc-amine);Fmoc-N-amido-PEG12-propionic acid;(Fmoc-amino)-PEG12-C2-Carboxylic Acid
- CBNumber:
- CB53371186
- Molecular Formula:
- C42H65NO16
- Molecular Weight:
- 839.96
- MDL Number:
- MOL File:
- 1952360-91-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 870.4±65.0 °C(Predicted) |
|---|---|
| Density | 1.175±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| form | clear liquid |
| pka | 4.28±0.10(Predicted) |
| color | Colorless to Light yellow |
| InChIKey | JYNHRDJTWNEGJE-UHFFFAOYSA-N |
| SMILES | C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| HS Code | 2924297099 | |||||||||
| NFPA 704 |
|
Fmoc-NH-PEG12-CH2CH2COOH price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F1238 | (Fmoc-amino)-PEG12-C2-Carboxylic Acid | 1952360-91-6 | 100MG | $285 | 2026-04-30 | Buy |
| Biosynth | CDD36091 | (Fmoc-amino)-PEG12-C2-carboxylic acid | 1952360-91-6 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | CDD36091 | (Fmoc-amino)-PEG12-C2-carboxylic acid | 1952360-91-6 | 1g | $900 | 2026-06-04 | Buy |
| Biosynth | CDD36091 | (Fmoc-amino)-PEG12-C2-carboxylic acid | 1952360-91-6 | 10g | $1038.4 | 2026-06-04 | Buy |
| Biosynth | CDD36091 | (Fmoc-amino)-PEG12-C2-carboxylic acid | 1952360-91-6 | 25g | $1947 | 2026-06-04 | Buy |
Fmoc-NH-PEG12-CH2CH2COOH Chemical Properties, Uses, Production
Purity
＞98%
Description
Fmoc-NH-PEG12-CH2CH2COOH (CAS 1952360-91-6), also known as Fmoc-N-amido-PEG12-acid, Fmoc-NH-PEG(12)-COOH, (Fmoc-amino)-PEG12-C2-Carboxylic Acid and FmocNH-PEG12-CH2CH2COOH, is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
General Description
FmocNH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker. Fmoc-NH-PEG12-CH2CH2COOH can be used in the synthesis of PROTAC.
Hazard
Fmoc-NH-PEG12-CH2CH2COOH is a irritant. Contact may cause skin irritation and severe eye irritation.
IC 50
PEGs
storage
Keep in dark place,Inert atmosphere,Store in freezer, under -20 ℃.
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-NH-PEG12-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-NH-PEG12-CH2CH2COOH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Bairuikang Biotechnology Co., Ltd. | 18168036974 | wangweicss@126.com | China | 1379 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 18217049878 | cassie.gao@pu-kang.com | China | 480 | 58 |
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 988 | 59 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2980 | 58 |
| Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd. | 19981275275 | sales@zsdpharm.com | China | 388 | 58 |
| Affinity Linkers Ltd. | 15841022315 15841022315 | sales@affinitytech.cn | China | 7039 | 58 |
| Changsha Morning Shine Co., Ltd. | 189-75832125 13397510867 | BD@csmspharm.com | China | 552 | 58 |
| Yangzhou Jide Kangrui Biotechnology Co., Ltd. | 15029750239 | 1002921772@qq.com | China | 1009 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
View Latest Price from Fmoc-NH-PEG12-CH2CH2COOH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-28 | Fmoc-NH-PEG12-CH2CH2COOH
1952360-91-6
|
1g | 98% | 300kg | LAURENT | ||
 |
2025-06-07 | Fmoc-N-amido-PEG12-acid
1952360-91-6
|
5g | >99.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-
- Fmoc-NH-PEG12-CH2CH2COOH
1952360-91-6
- 98%
- LAURENT
-
- Fmoc-N-amido-PEG12-acid
1952360-91-6
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
