3-Azidopropanoic acid NHS ester
- CAS No.
- 850180-76-6
- Chemical Name:
- 3-Azidopropanoic acid NHS ester
- Synonyms
- N3-C2-NHS ester;3-Azidopropanoic acid NHS ester;(2,5-Dioxopyrrolidin-1-yl) 3-azidopropanoate;3-azidopropanoate-N-hydroxysuccinimide ester;(2,5-Dioxopyrrolidin-1-yl) 3-azidopropanoate - [A19129]
- CBNumber:
- CB53373524
- Molecular Formula:
- C7H8N4O4
- Molecular Weight:
- 212.17
- MDL Number:
- MFCD24452814
- MOL File:
- 850180-76-6.mol
- MSDS File:
- SDS
3-Azidopropanoic acid NHS ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | AJB18076 | 3-Azidopropanoate-N-hydroxysuccinimide ester | 850180-76-6 | 25mg | $221.25 | 2026-06-04 | Buy |
| Biosynth | AJB18076 | 3-Azidopropanoate-N-hydroxysuccinimide ester | 850180-76-6 | 50mg | $354.5 | 2026-06-04 | Buy |
| Biosynth | AJB18076 | 3-Azidopropanoate-N-hydroxysuccinimide ester | 850180-76-6 | 100mg | $565 | 2026-06-04 | Buy |
| Biosynth | AJB18076 | 3-Azidopropanoate-N-hydroxysuccinimide ester | 850180-76-6 | 250mg | $1065 | 2026-06-04 | Buy |
| Biosynth | AJB18076 | 3-Azidopropanoate-N-hydroxysuccinimide ester | 850180-76-6 | 500mg | $1715 | 2026-06-04 | Buy |
3-Azidopropanoic acid NHS ester Chemical Properties, Uses, Production
Description
3-Azidopropanoic acid NHS ester is an azidopropanoic acid linker that contains an NHS ester group. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkyne, DBCO and BCN. The NHS ester can react with other primary amines to label proteins and antibodies.
Uses
N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Non-cleavable Linker
References
[1] Gregson SJ, et al. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507. DOI:10.1021/acs.jmedchem.7b00736
3-Azidopropanoic acid NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
3-Azidopropanoic acid NHS ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 3927209986@qq.com | China | 9999 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3147 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Hangzhou Synmed Pharmatech Co., Ltd. | 0571-56361269 17721302038 | sales@synmed.cn | China | 116 | 58 |
| Wuhan Shanhai Zhihe Biotechnology Co., Ltd. | 17771424646 | shoubull@126.com | China | 892 | 58 |
View Latest Price from 3-Azidopropanoic acid NHS ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | N3-C2-NHS ester
850180-76-6
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | N3-C2-NHS ester
850180-76-6
|
250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- N3-C2-NHS ester
850180-76-6
- $0.00
- TargetMol Chemicals Inc.
-
- N3-C2-NHS ester
850180-76-6
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
