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4-Aminoguinoline

CAS No.
578-68-7
Chemical Name:
4-Aminoguinoline
Synonyms
Quinolin-4-amine;4-AMINOQUINOLINE;4-Quinolylamine;4-QUINOLINAMINE;4-Aminoguinoline;QUINOLIN-4-YLAMINE;4(1H)-Quinolinimine;4-Aminoquinoline 95+%;4-Aminoquinoline ,98%;4-Aminoquinoline, 97.5%
CBNumber:
CB5339468
Molecular Formula:
C9H8N2
Molecular Weight:
144.17
MDL Number:
MFCD00463448
MOL File:
578-68-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:24:10

4-Aminoguinoline Properties

Melting point 151.0 and le 155.0 °C
Boiling point 312.78°C (estimate)
Density 1.1148 (estimate)
refractive index 1.7080 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 9.17(at 20℃)
form powder to crystalline
color White to Yellow to Orange
InChI InChI=1S/C9H8N2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H,(H2,10,11)
InChIKey FQYRLEXKXQRZDH-UHFFFAOYSA-N
SMILES N1C2C(=CC=CC=2)C(N)=CC=1
CAS DataBase Reference 578-68-7(CAS DataBase Reference)
FDA UNII GTE5P5L97N
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38-36-22-41
Safety Statements  26-36/37/39-39
RIDADR  2811
WGK Germany  WGK 3
HS Code  29334900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
NFPA 704
0
2 0

4-Aminoguinoline price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS009704 4-aminoquinoline AldrichCPR 578-68-7 100 mg $114 2026-04-30 Buy
Sigma-Aldrich BBO000743 4-Aminoquinoline 578-68-7 1 g $230 2026-04-30 Buy
TCI Chemical A2600 4-Aminoquinoline >98.0%(GC)(T) 578-68-7 1g $83 2026-04-30 Buy
Usbiological 260164 4-amino-quinoline Asreported 578-68-7 1g $455 2026-06-03 Buy
Usbiological 260164 4-amino-quinoline Asreported 578-68-7 2g $664 2026-06-03 Buy
Product number Packaging Price Buy
CDS009704 100 mg $114 Buy
BBO000743 1 g $230 Buy
A2600 1g $83 Buy
260164 1g $455 Buy
260164 2g $664 Buy

4-Aminoguinoline Chemical Properties, Uses, Production

Preparation

Research has found that, under transition metal-free conditions, a series of 4-Aminoguinoline and their derivatives can be synthesized via a three-component one-pot method using amines, benzenesulfonyl acetonitrile, and dimethyl sulfoxide as substrates through catalytic oxidation cyclization reactions.

Chemical Properties

Light brown to grey solid

Uses

4-Quinolinamine and its derivatives are commonly used as anti-malarial drugs and also have potential therapeutic effects on patients afflicted with arthritis (and/or related diseases).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 43, p. 4667, 2000 DOI: 10.1021/jm0002073
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2

Purification Methods

It has been purified by zone refining and recrystallisation from *C6H6, EtOH or H2O. The hydrochloride has m 308o (from MeOH), and the picrate has m 277o (from EtOH). [Albert et al. J Chem Soc 2240 1948, Beilstein 22 III/IV 4611, 22/10 V 341.]

Global Suppliers ( 197)
Supplier Tel Email Country ProdList Advantage
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59

View Latest Price from 4-Aminoguinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Aminoguinoline  pictures 2026-08-20 4-Aminoguinoline
578-68-7
$1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
4-Aminoguinoline pictures 2025-04-04 4-Aminoguinoline
578-68-7
1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-Aminoguinoline pictures 2019-07-06 4-Aminoguinoline
578-68-7
$1.00 1kg 98% 200kg Career Henan Chemical Co
4-AMinoquinoline hydrochloride QUINOLIN-4-YLAMINE 4-QUINOLINAMINE 4-Quinolylamine 4-Aminoguinoline 4-Aminoquinoline ,98% 4-Aminoquinoline 95+% 4-Aminoquinoline, 97.5% 4(1H)-Quinolinimine 4-Aminoguinoline ISO 9001:2015 REACH Benzenemethanamine,5-bromo-5-chloro- 5-Benzofuransulfonylchloride,2,7-dihydro- 4-AMINOQUINOLINE Quinolin-4-amine 578-68-7 pharmacetical