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ChemicalBook >> CAS DataBase List >>2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol Structure
2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol structure
CAS No.
881914-35-8
Chemical Name:
2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol
Synonyms
2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol;1,3-Propanediol, 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]-
CBNumber:
CB53775933
Molecular Formula:
C19H32N4O2
Molecular Weight:
348.48298
MDL Number:
MOL File:
881914-35-8.mol
MSDS File:
SDS
Last updated:2026-07-17 09:03:53
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2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol Properties

Melting point 63-65 °C
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2) (1:1): .2 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 881914-35-8 100μg $37 2026-04-30 Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 881914-35-8 500μg $158 2026-04-30 Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 881914-35-8 1mg $280 2026-04-30 Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 881914-35-8 5mg $1216 2026-04-30 Buy
Biosynth GKB91435 Azido-FTY720 881914-35-8 5mg $1835.1 2026-06-04 Buy
Product number Packaging Price Buy
10008612 100μg $37 Buy
10008612 500μg $158 Buy
10008612 1mg $280 Buy
10008612 5mg $1216 Buy
GKB91435 5mg $1835.1 Buy

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol Chemical Properties, Uses, Production

Description

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.1 FTY720 is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5).2 Down-regulation of S1P1 receptors on T and B lymphocytes by FTY720 results in defective egress of these cells from spleen, lymph nodes, and Peyer’s patch.3 azido-FTY720 is a highly photoreactive analog of FTY720 that can be used to identify receptor binding sites for this ligand.4

Uses

Azido-FTY720 is a photoactivatable analogue of FTY720. Azido-FTY720 is used for identifying binding sites between FTY720 and its receptors[1]. Azido-FTY720 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

1. Brinkmann, V., Pinschewer, D.D., Feng, L., et al. FTY720: Altered lymphocyte traffic results in allograft protection Transplantation 72(5),764-769(2001).
2. Brinkmann, V., Davis, M.D., Heise, C.E., et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors J. Biol. Chem. 277(24),21453-21457(2002).
3. Matloubian, M., Lo, C.G., Cinamon, G., et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 Nature 427(6972),355-360(2004).
4. Sun, C., and Bittman, R. A photoreactive analogue of the immunosuppressant FTY720 J. Org. Chem. 71,2200-2202(2006).

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38923 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58

View Latest Price from 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Azido-FTY720 pictures 2026-07-17 Azido-FTY720
881914-35-8
 $920.00-3920.00 10g TargetMol Chemicals Inc.
  • Azido-FTY720 pictures
  • Azido-FTY720
    881914-35-8
  • $920.00-3920.00
  • TargetMol Chemicals Inc.

881914-35-8 (2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol) Related Search:

1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) FTY720 (R)-Phosphate (S) FTY720 PHOSPHATE FTY720 phenoxy-biotin racFTY720 Phosphate
HATU

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2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol 1,3-Propanediol, 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]- 881914-35-8