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Arg-Lys-Glu-Val-Tyr acetate salt

Arg-Lys-Glu-Val-Tyr acetate salt structure

CAS No.: 105184-37-0

Chemical Name:: Arg-Lys-Glu-Val-Tyr acetate salt

Synonyms: SP-5 ACETATE SALT;Splenopentin diacetate;Splenopentin Acetate L;SPLENOPENTIN ACETATE SALT;ARG-LYS-GLU-VAL-TYR ACETATE;Splenopentin diacetate salt;SP-5, Splenin Fragment 32-36;Splenin pentapeptide (32-36);Arg-Lys-Glu-Val-Tyr acetate salt;SPLENIN FRAGMENT 32-36 ACETATE SALT

CBNumber:: CB5384574

Molecular Formula:: C33H55N9O11

Molecular Weight:: 753.84

MDL Number:: MFCD00133108

MOL File:: 105184-37-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:53:31

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Arg-Lys-Glu-Val-Tyr acetate salt Properties

storage temp.	−20°C

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338
WGK Germany	3

Arg-Lys-Glu-Val-Tyr acetate salt price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0017922	Splenopentin diacetate	105184-37-0	1mg	$37	2026-06-04	Buy
aablocks	AA01EH4Q	Splenopentin (diacetate)	105184-37-0	2mg	$35	2026-05-30	Buy
aablocks	AA01EH4Q	Splenopentin (diacetate)	105184-37-0	5mg	$45	2026-05-30	Buy
aablocks	AA01EH4Q	Splenopentin (diacetate)	105184-37-0	10mg	$57	2026-05-30	Buy
aablocks	AA01EH4Q	Splenopentin (diacetate)	105184-37-0	25mg	$83	2026-05-30	Buy

Product number	Packaging	Price	Buy
CS-0017922	1mg	$37	Buy
AA01EH4Q	2mg	$35	Buy
AA01EH4Q	5mg	$45	Buy
AA01EH4Q	10mg	$57	Buy
AA01EH4Q	25mg	$83	Buy

Arg-Lys-Glu-Val-Tyr acetate salt Chemical Properties,Uses,Production

Uses

Splenopentin diacetate is a synthetic immunomodulating pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin. Splenopentin diacetate influences both early T and B cell differentiation, to increase the number of antibody-forming cells in mice after gamma irradiation[1][2].

Biological Activity

Splenopentin diacetate is a synthetic immunomodulatory pentapeptide corresponding to residues 32-36 of the spleen hormone spleen protein. It affects early T and B cell differentiation, thereby increasing the number of antibody-forming cells in gamma-irradiated mice.

in vitro

Splenopentin (1-100 μM) augments human NK cells and has no cytotoxicity.
Splenopentin (0.1 ng/mL-10 μg/mL; 3 h) induces phenotypic differentiation of both T- and B -cell precursor cells.

in vivo

Splenopentin (1 mg/kg; ip three times a week for 7-90 d) accelerates Langerhans cell recruitment and leads to pretreatment levels of Langerhans cell (LC) density in the skin of mice.
Splenopentin (0.01-100 μg per mouse; ip) has no demonstrable effect on neuromuscular transmission of mice.

Animal Model:	Female Balb /c/Bln mice were injected Cyclophosphamide or Dexamethasone for 5 consecutive days
Dosage:	1 mg /kg
Administration:	Ip three times a week for 7-90 days
Result:	Reached the normal number of epidermal LCs at 28 days after the beginning of Cyclophosphamide treatment. Accelerated restoration process and reached the normal LC density in the skin after 70 days in Dexamethasone treatment grops.

References

[1] Singh VK, et, al. Thymopentin and splenopentin as immunomodulators. Current status. Immunol Res. 1998;17(3):345-68. DOI:10.1007/BF02786456
[2] Rastogi A, et, al. Augmentation of human natural killer cells by splenopentin analogs. FEBS Lett. 1993 Feb 8;317(1-2):93-5. DOI:10.1016/0014-5793(93)81498-o
[3] Audhya T, et, al. Contrasting biological activities of thymopoietin and splenin, two closely related polypeptide products of thymus and spleen. Proc Natl Acad Sci U S A. 1984 May;81(9):2847-9. DOI:10.1073/pnas.81.9.2847
[4] Gruner S, et, al. Stimulation of the recruitment of epidermal Langerhans cells by splenopentin. Arch Dermatol Res. 1990;281(8):526-9. DOI:10.1007/BF00412738

Arg-Lys-Glu-Val-Tyr acetate salt Preparation Products And Raw materials

Raw materials

Preparation Products

Arg-Lys-Glu-Val-Tyr acetate salt Suppliers

Global( 108)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
NINGBO INNO PHARMCHEM CO.,LTD.	86-574-27787657	info@dearchem.com	China	4607	58
Shanghai YuLue Chemical Co., Ltd.	021-60345187 13671753212	lzz841106@aliyun.com	China	10244	55
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9781	50
Credit Asia Chemical Co., Ltd.	+86 (21) 61124340		China	9739	58
Hubei Jusheng Technology Co.,Ltd	027-59599241 18871490274	1400878000@qq.com	China	9506	58
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2374	58
AN PharmaTech Co Ltd	86(21)68097365	sales@anpharma.net	China	4875	55
Creative Peptides		info@creative-peptides.com	United States	6083	56

Supplier	Advantage
GL Biochem (Shanghai) Ltd	64
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
NINGBO INNO PHARMCHEM CO.,LTD.	58
Shanghai YuLue Chemical Co., Ltd.	55
Shanghai HuanChuan Industry Co.,Ltd.	50
Credit Asia Chemical Co., Ltd.	58
Hubei Jusheng Technology Co.,Ltd	58
LETOPHARM LIMITED	58
AN PharmaTech Co Ltd	55
Creative Peptides	56

View Lastest Price from Arg-Lys-Glu-Val-Tyr acetate salt manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-11	Splenopentin diacetate 105184-37-0	$30.00-68.00		99.90%	10g	TargetMol Chemicals Inc.
2025-04-04	ARG-LYS-GLU-VAL-TYR ACETATE SALT 105184-37-0		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-07-13	Splenopentin Acetate 105184-37-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Splenopentin diacetate
105184-37-0
$30.00-68.00
99.90%
TargetMol Chemicals Inc.

ARG-LYS-GLU-VAL-TYR ACETATE SALT
105184-37-0
98%
Henan Aochuang Chemical Co.,Ltd.

Splenopentin Acetate
105184-37-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

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