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SIB 1893

SIB 1893 Structure
SIB 1893 structure
CAS No.
6266-99-5
Chemical Name:
SIB 1893
Synonyms
SIB 1893;NSC 36665;(E/Z)-SIB-1893;(E/Z)SIB1893,(E/Z) SIB 1893;(E)-2-METHYL-6-STYRYL-PYRIDINE;2-METHYL-6-(2-PHENYLETHENYL)PYRIDINE;(E)-2-METHYL-6-(2-PHENYLETHYL)-PYRIDINE;Pyridine, 2-methyl-6-(2-phenylethenyl)-;2-Methyl-6-[(E)-2-phenylethenyl]pyridine
CBNumber:
CB5393055
Molecular Formula:
C14H13N
Molecular Weight:
195.26
MDL Number:
MFCD02262120
MOL File:
6266-99-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
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SIB 1893 Properties

storage temp. 2-8°C
solubility DMSO: 18 mg/mL
form solid
color White to off-white
FDA UNII 4X2F5X24UK

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

SIB 1893 price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 466078 SIB 1893 6266-99-5 10mg $355 2026-06-03 Buy
Usbiological 466078 SIB 1893 6266-99-5 25mg $531 2026-06-03 Buy
Usbiological 256664 SIB 1893 Asreported 6266-99-5 10mg $389 2026-06-03 Buy
Usbiological 256664 SIB 1893 Asreported 6266-99-5 50mg $905 2026-06-03 Buy
Biosynth GAA26699 SIB 1893 6266-99-5 50mg $787 2026-06-04 Buy
Product number Packaging Price Buy
466078 10mg $355 Buy
466078 25mg $531 Buy
256664 10mg $389 Buy
256664 50mg $905 Buy
GAA26699 50mg $787 Buy

SIB 1893 Chemical Properties, Uses, Production

Uses

SIB 1893 is a selective antagonist of mGluR-5. SIB 1893 acts as a positive allosteric modulator of human metabotropic mGlu4 (1). Anticonvulsant (2).

Definition

ChEBI: 2-methyl-6-(2-phenylethenyl)pyridine is a member of styrenes.

Biological Activity

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu 5 receptor subtype; displays an IC 50 value of 0.3 μ M at hmGlu 5 , compared with > 100 μ M at hmGlu 1b , hmGlu 2 , hmGlu 6 , hmGlu 7 and hmGlu 8 . Centrally active upon systemic administration in vivo . Positive allosteric modulator at mGlu 4 receptors.

in vivo

(E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner[1].

SIB 1893 Preparation Products And Raw materials

Raw materials

Preparation Products

SIB 1893 Suppliers

Global Suppliers ( 55)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 1999 58
AdooQ Bioscience CHINA 025-58849295 info@adooq.cn China 2981 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9780 55
Capot Chemical Co.,Ltd. +86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Alfa Chemistry +1-5166625404; Info@alfa-chemistry.com United States 20000 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
HangZhou YuHao Chemical Technology Co., Ltd. 58
AdooQ Bioscience CHINA 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Capot Chemical Co.,Ltd. 60
Alfa Chemistry 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
MedBioPharmaceutical Technology Inc 58

View Latest Price from SIB 1893 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(E/Z)-SIB-1893 pictures 2026-04-22 (E/Z)-SIB-1893
6266-99-5
 $67.00-247.00 99.96% 10g TargetMol Chemicals Inc.

SIB 1893 Spectrum

SIB 1893(6266-99-5)1HNMR

6266-99-5 (SIB 1893) Related Search:

ETHYLENE stilbazium iodide SIB 1893 4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(3-chlorophenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(4-chlorophenyl)ethenyl]-5H-indeno[1,2-b]pyridin-5-one
4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 2-[(E)-2-(3-Chlorophenyl)ethenyl]-4-(4-heptylphenyl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(3-bromophenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(3-nitrophenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(2-Fluorophenyl)-2-[(E)-2-(3-methoxyphenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile
4-(1,3-Benzodioxol-5-yl)-2-(4-methoxystyryl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(2-chlorophenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-(3,4-dichlorostyryl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-[(E)-2-(2-fluorophenyl)ethenyl]-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 4-(1,3-Benzodioxol-5-yl)-2-(4-hydroxystyryl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile
4-(1,3-Benzodioxol-5-yl)-2-(4-nitrostyryl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 2-[(E)-2-(4-Fluorophenyl)ethenyl]-5-oxo-4-(3,4,5-trimethoxyphenyl)-5H-indeno[1,2-b]pyridine-3-carbonitrile

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SIB 1893 2-METHYL-6-(2-PHENYLETHENYL)PYRIDINE (E)-2-METHYL-6-(2-PHENYLETHYL)-PYRIDINE (E)-2-METHYL-6-STYRYL-PYRIDINE 2-Methyl-6-[(E)-2-phenylethenyl]pyridine NSC 36665 Pyridine, 2-methyl-6-(2-phenylethenyl)- (E/Z)-SIB-1893 (E/Z)SIB1893,(E/Z) SIB 1893 6266-99-5 Glutamate receptor