Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-(2-Bromo-4-fluoro-phenyl)-propionic acid

3-(2-Bromo-4-fluoro-phenyl)-propionic acid

3-(2-Bromo-4-fluoro-phenyl)-propionic acid Structure
3-(2-Bromo-4-fluoro-phenyl)-propionic acid structure
CAS No.
174603-55-5
Chemical Name:
3-(2-Bromo-4-fluoro-phenyl)-propionic acid
Synonyms
3-Chloro-2-fluoro-phenylalanine;Benzenepropanoic acid, 2-broMo-4-fluoro-;3-(2-broMo-4-fluorophenyl)propanoic acid;3-(2-Bromo-4-fluoro-phenyl)-propionic acid
CBNumber:
CB5407611
Molecular Formula:
C9H8BrFO2
Molecular Weight:
247.06
MDL Number:
MFCD06656907
MOL File:
174603-55-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:31
Request For Quotation

3-(2-Bromo-4-fluoro-phenyl)-propionic acid Properties

Boiling point 331.4±27.0 °C(Predicted)
Density 1.606±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 4.59±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3-(2-Bromo-4-fluoro-phenyl)-propionic acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS118441 3-(2-Bromo-4-fluorophenyl)propionic acid 95% 174603-55-5 1g $162 2026-06-04 Buy
Activate Scientific AS118441 3-(2-Bromo-4-fluorophenyl)propionic acid 95% 174603-55-5 5g $503 2026-06-04 Buy
Matrix Scientific 301756 3-(2-Bromo-4-fluorophenyl)propionic acid 174603-55-5 250.00mg $34 2026-05-19 Buy
Matrix Scientific 301756 3-(2-Bromo-4-fluorophenyl)propionic acid 174603-55-5 1.00g $102 2026-05-19 Buy
Matrix Scientific 301756 3-(2-Bromo-4-fluorophenyl)propionic acid 174603-55-5 5.00g $506 2026-05-19 Buy
Product number Packaging Price Buy
AS118441 1g $162 Buy
AS118441 5g $503 Buy
301756 250.00mg $34 Buy
301756 1.00g $102 Buy
301756 5.00g $506 Buy

3-(2-Bromo-4-fluoro-phenyl)-propionic acid Chemical Properties, Uses, Production

Synthesis

Propanedioic acid, 2-[(2-bromo-4-fluorophenyl)methyl]-, 1,3-diethyl ester

174603-54-4

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID

174603-55-5

Diethyl 2-(2-bromo-4-fluorobenzyl)-malonate (2.1 g, 6.07 mmol) was used as a raw material, which was mixed with water (14 mL) and potassium hydroxide (0.68 g, 12.14 mmol) was added. The reaction mixture was heated under reflux conditions for 4.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and ethanol was removed by distillation under reduced pressure. The aqueous residue was cooled to 100°C, acidified with concentrated sulfuric acid and subsequently heated at 120°C for 16 hours. After the reaction mixture was cooled to 0°C, the precipitated solid was collected by filtration, washed with water and dried to afford 3-(2-bromo-4-fluorophenyl)propionic acid as an off-white solid (0.5 g, 33% yield). Thin layer chromatography (TLC) showed an Rf value of 0.2 (unfolding agent: 30% ethyl acetate/petroleum ether).1H NMR (400 MHz, DMSO-d6) data were as follows: δ 12.26 (s, 1H), 7.55-7.52 (m, 1H), 7.42-7.38 (m, 1H), 7.23-7.18 (m, 1H), 2.90 (t. J = 7.8 Hz, 2H), 2.52 (t, J = 7.8 Hz, 2H).

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 409 - 416
[2] Patent: WO2015/36759, 2015, A1. Location in patent: Page/Page column 171

3-(2-Bromo-4-fluoro-phenyl)-propionic acid Preparation Products And Raw materials

Raw materials

Propanedioic acid, 2-[(2-bromo-4-fluorophenyl)methyl]-, 1,3-diethyl ester

Preparation Products

4-Bromo-6-fluoroindan-1-one

3-(2-Bromo-4-fluoro-phenyl)-propionic acid Suppliers

Global Suppliers ( 51)
Supplier Tel Email Country ProdList Advantage
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
SynAsst Chemical. 021-60343070 China 12731 55
Acesys Pharmatech 18860950986 tangmanman@zenjipharma.com China 1731 55
Shanghai JONLN Reagent Co., Ltd. 400-0066400 13621662912 422131432@qq.com China 9970 55
NINGBO INNO PHARMCHEM CO.,LTD. 86-574-27787657 info@dearchem.com China 4607 58
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Supplier Advantage
Chembest Research Laboratories Limited 61
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Adamas Reagent, Ltd. 59
Hangzhou Sage Chemical Co., Ltd. 58
Nanjing Norris-Pharm Technology Co., Ltd 55
SynAsst Chemical. 55
Acesys Pharmatech 55
Shanghai JONLN Reagent Co., Ltd. 55
NINGBO INNO PHARMCHEM CO.,LTD. 58
Shanghai HuanChuan Industry Co.,Ltd. 50

View Latest Price from 3-(2-Bromo-4-fluoro-phenyl)-propionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(2-Bromo-4-fluorophenyl)propionic acid pictures 2020-02-01 3-(2-Bromo-4-fluorophenyl)propionic acid
174603-55-5
 $1.00 1KG Min98% HPLC Career Henan Chemical Co

3-(2-Bromo-4-fluoro-phenyl)-propionic acid Spectrum

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID(174603-55-5)1HNMR

174603-55-5 (3-(2-Bromo-4-fluoro-phenyl)-propionic acid) Related Search:

3-(2-Bromo-4-fluoro-phenyl)-propionic acid ethyl ester Methyl (2S)-2-amino-3-(2-bromo-4-fluorophenyl)propanoate Methyl (2R)-2-amino-3-(2-bromo-4-fluorophenyl)propanoate Methyl (3S)-3-amino-3-(2-bromo-4-fluorophenyl)propanoate Methyl (3R)-3-amino-3-(2-bromo-4-fluorophenyl)propanoate
3-(2-Bromo-4-fluoro-phenyl)-propionic acid Ethyl 3-amino-3-(2-bromo-4-fluorophenyl)propanoate hydrochloride 2-amino-3-(2-bromo-4-fluorophenyl)propanoic acid RARECHEM AL BL 1062

1of2

3-(2-broMo-4-fluorophenyl)propanoic acid Benzenepropanoic acid, 2-broMo-4-fluoro- 3-Chloro-2-fluoro-phenylalanine 3-(2-Bromo-4-fluoro-phenyl)-propionic acid 174603-55-5