Chlorotripyrrolidinophosphonium hexafluorophosphate
- CAS No.
- 133894-48-1
- Chemical Name:
- Chlorotripyrrolidinophosphonium hexafluorophosphate
- Synonyms
- PYCLOP;PYCIOP;REF DUPL: PyClOP;Chlorotripyrrolidino;Chlorotripyrrolidinop;Chlorotripyrrolidinophosphonium;Chlorotriphenylalkyl hexafluorophosphate;Chlorotripyrrolidinophosphoniumhexafluorophosphat;CHLOROTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;Chlorotriphyrrolidinyl hexafluorophosphate (PYCLOP)
- CBNumber:
- CB5408289
- Molecular Formula:
- C12H24ClF6N3P2
- Molecular Weight:
- 421.73
- MDL Number:
- MFCD00210035
- MOL File:
- 133894-48-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Chlorotripyrrolidinophosphonium hexafluorophosphate ≥98.0% (AT) | 26564 | 25g | $376 |
| Chlorotripyrrolidinophosphonium hexafluorophosphate ≥98.0% (AT) | 26564 | 5G | $118 |
| Chlorotripyrrolidinophosphonium Hexafluorophosphate >98.0%(HPLC)(T) | C2551 | 5g | $60 |
| Chlorotripyrrolidinophosphonium Hexafluorophosphate >98.0%(HPLC)(T) | C2551 | 25g | $311 |
| Chlorotripyrrolidinophosphonium hexafluorophosphate98+% ≥98% | 236865 | 1g | $170 |
| More product size | |||
| Melting point | 145-148°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform, Methanol |
| form | Crystalline Powder |
| color | White to yellow |
| Sensitive | Moisture Sensitive |
| BRN | 6842341 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C12H24ClN3P.F6P/c13-17(14-7-1-2-8-14,15-9-3-4-10-15)16-11-5-6-12-16;1-7(2,3,4,5)6/h1-12H2;/q+1;-1 |
| InChIKey | BSCYRXJVGSZNKX-UHFFFAOYSA-N |
| SMILES | [P+5]([F-])([F-])([F-])([F-])([F-])[F-].[P+](N1CCCC1)(N1CCCC1)(N1CCCC1)Cl |
| CAS DataBase Reference | 133894-48-1(CAS DataBase Reference) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318-H314 | |||||||||
| Precautionary statements | P260-P264-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P280-P305+P351+P338-P310-P260h-P301+P330+P331-P303+P361+P353-P501a | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | Xi,C | |||||||||
| Risk Statements | 36/37/38-34 | |||||||||
| Safety Statements | 26-36-45-36/37/39 | |||||||||
| RIDADR | UN 1759 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Chlorotripyrrolidinophosphonium hexafluorophosphate price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 26564 | Chlorotripyrrolidinophosphonium hexafluorophosphate ≥98.0% (AT) | 133894-48-1 | 25g | $376 | 2026-04-30 | Buy |
| Sigma-Aldrich | 26564 | Chlorotripyrrolidinophosphonium hexafluorophosphate ≥98.0% (AT) | 133894-48-1 | 5G | $118 | 2023-06-20 | Buy |
| TCI Chemical | C2551 | Chlorotripyrrolidinophosphonium Hexafluorophosphate >98.0%(HPLC)(T) | 133894-48-1 | 5g | $60 | 2026-04-30 | Buy |
| TCI Chemical | C2551 | Chlorotripyrrolidinophosphonium Hexafluorophosphate >98.0%(HPLC)(T) | 133894-48-1 | 25g | $311 | 2023-06-20 | Buy |
| Usbiological | 236865 | Chlorotripyrrolidinophosphonium hexafluorophosphate98+% ≥98% | 1g | $170 | 2026-06-03 | Buy |
Chlorotripyrrolidinophosphonium hexafluorophosphate Chemical Properties,Uses,Production
Uses
Crystalline reagent for peptide coupling of a-alkylated N-Fmoc and N-Z-amino acids in high yield and without racemization.
Uses
Reagent for:
Peptide coupling reactions and synthesis of coupling reagents
Sequence selective peptide recognition
Synthesis of condensing reagents
Synthesis of heterocyclic β-sheet ligands
Preparation
Preparation of chlorotripyrrolidinophosphonium hexafluorophosphate: addition of chlorine to a diethyl ether solution of tripyrrolidinophosphine, then addition of KPF6 in water. Addition of tripyrrolidinophosphine oxide to a DCM solution of phosphoryl trichloride, then addition of KPF6 in water.
reaction suitability
reaction type: Coupling Reactions
Chlorotripyrrolidinophosphonium hexafluorophosphate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Highfine Biotech Co.,Ltd. | +86-0512-68071238 +86-13771819922 | june@highfine.com | China | 491 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +8617792793228 | 1090@dideu.com | China | 8660 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29094 | 58 |
View Lastest Price from Chlorotripyrrolidinophosphonium hexafluorophosphate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-16 | Chlorotripyrrolidinophosphonium hexafluorophosphate
133894-48-1
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-06-05 | PyCIOP
133894-48-1
|
$1.50 | 1g | 99.0% Min | 10 Tons | Shaanxi Didu New Materials Co. Ltd | |
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2025-04-04 | Chlorotripyrrolidinophosphonium hexafluorophosphate
133894-48-1
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
-

- Chlorotripyrrolidinophosphonium hexafluorophosphate
133894-48-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- PyCIOP
133894-48-1
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-

- Chlorotripyrrolidinophosphonium hexafluorophosphate
133894-48-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.





