ChemicalBook >> CAS DataBase List >>1,4-Phenylene diisocyanate
1,4-Phenylene diisocyanate
- CAS No.
- 104-49-4
- Chemical Name:
- 1,4-Phenylene diisocyanate
- Synonyms
- PPDI;1,4-Diisocyanatobenzene;P-PHENYLENE DIISOCYANATE;1,4-PhenyL;FLURBIPROFEN USP24;1,4-Phenylene diisoc;p-phenyleneisocyanate;p-phenyl diisocyanate;Phenylene diisocyanat;1,4-Phenyldiisocyanate
- CBNumber:
- CB5409756
- Molecular Formula:
- C8H4N2O2
- Molecular Weight:
- 160.13
- MDL Number:
- MFCD00002025
- MOL File:
- 104-49-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-04 16:00:12
| Melting point | 96-99 °C (lit.) |
|---|---|
| Boiling point | 260 °C (lit.) |
| Density | 1.3848 (rough estimate) |
| vapor pressure | <0.01 mm Hg ( 20 °C) |
| refractive index | 1.4900 (estimate) |
| Flash point | >230 °F |
| solubility | THF: soluble |
| form | powder to crystal |
| color | White to Light yellow |
| Water Solubility | 130mg/L at 20℃ |
| Stability | Stable. Combustible. Incompatible with strong oxidising agents, strong alkalies, strong acids, alcohols, amines. Moisture sensitive. |
| InChI | 1S/C8H4N2O2/c11-5-9-7-1-2-8(4-3-7)10-6-12/h1-4H |
| InChIKey | ALQLPWJFHRMHIU-UHFFFAOYSA-N |
| SMILES | O=C=Nc1ccc(cc1)N=C=O |
| LogP | 3.19 at 20℃ |
| CAS DataBase Reference | 104-49-4(CAS DataBase Reference) |
| FDA UNII | OKE64XZR2L |
| NIST Chemistry Reference | Benzene, 1,4-diisocyanato-(104-49-4) |
| EPA Substance Registry System | 1,4-Phenylene diisocyanate (104-49-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H317-H319-H330-H334-H411 | |||||||||
| Precautionary statements | P260-P273-P280-P302+P352-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,C | |||||||||
| Risk Statements | 20/21/22-36/37/38-42-34-41-38 | |||||||||
| Safety Statements | 22-26-36/37-45-36/37/39 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CZ6150000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29291010 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Inhalation Aquatic Chronic 2 Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 Skin Sens. 1 |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 0.5 Kg (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
1,4-Phenylene diisocyanate price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 262242 | 1,4-Phenylene diisocyanate | 104-49-4 | 25g | $91.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 262242 | 1,4-Phenylene diisocyanate | 104-49-4 | 100g | $151 | 2026-04-30 | Buy |
| TCI Chemical | P1640 | 1,4-Phenylene Diisocyanate >98.0%(GC) | 104-49-4 | 25g | $130 | 2026-04-30 | Buy |
| TCI Chemical | P1640 | 1,4-Phenylene Diisocyanate >98.0%(GC) | 104-49-4 | 250g | $633 | 2026-04-30 | Buy |
| Strem Chemicals | 07-0101 | 1,4-Phenylene diisocyanate | 104-49-4 | 5g | $44 | 2026-04-30 | Buy |
1,4-Phenylene diisocyanate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystals
Uses
1,4-Phenylene diisocyanate has been used:
- as croos-linking reagent to investigate the mechanism of enzyme immobilization on silanized surfaces
- in the synthesis of dipodal bis-urea receptor, a selective receptor for hydrogen sulfate
- in deposition of polyurea resists films via molecular layer deposition
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 7, p. 177, 1970 DOI: 10.1002/jhet.5570070126
General Description
White crystals or pale yellow chunky solid. Pungent odor.
Air & Water Reactions
Reacts slowly with water to form CO2
Reactivity Profile
1,4-Phenylene diisocyanate is sensitive to moisture. 1,4-Phenylene diisocyanate is incompatible with water, strong acids, strong alkalis, strong oxidizers, alcohol, amines and other hydrogen compounds.
Fire Hazard
1,4-Phenylene diisocyanate is combustible.
Flammability and Explosibility
Not classified
1,4-Phenylene diisocyanate Preparation Products And Raw materials
Global( 301)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianmen Hengchang Chemical Co., Ltd | 027-59322316 15172518801 | 1208480077@qq.com | China | 9485 | 58 |
| Wuhan Huajiu Pharmaceutical Technology Co.,Ltd. | 027-59225746 18062681621 | 730880265@qq.com | China | 4800 | 58 |
| Jiangsu Haolong Chemical Co., Ltd | 0513-89083520 13328092525 | 2363930984@qq.com | China | 2054 | 58 |
| Shenzhen Xingkaiyue Biotechnology Co. , Ltd. | 0755-18589069862 18589069862 | 1158168052@qq.com | China | 1000 | 58 |
| Hubei Chanmol Biotech Co., Ltd. | 0711-3812399 18062309155 | 156941107@qq.com | China | 2975 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Lastest Price from 1,4-Phenylene diisocyanate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 1,4-Phenylene diisocyanate
104-49-4
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | 1,4-Phenylene diisocyanate
104-49-4
|
$1.00 | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-08-15 | 1,4-Phenylene diisocyanate
104-49-4
|
$1.00 | 10g | 99% | 80000g | Hebei Anlijie Biotechnology Co., Ltd |
-
- 1,4-Phenylene diisocyanate
104-49-4
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 1,4-Phenylene diisocyanate
104-49-4
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1,4-Phenylene diisocyanate
104-49-4
- $1.00
- 99%
- Hebei Anlijie Biotechnology Co., Ltd
104-49-4(1,4-Phenylene diisocyanate)Related Search:
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4,4'-phenyl isocyanate
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1,4-PhenyL
1,4-Phenylene diisocyanate 104-49-4
104-49-4 p-Phenylene diisocyanate
Phenylene diisocyanat
1,4-Phenylene diisocyate
BENZENE 1,4-DIISOCYANATE
1,4-PHENYLENE DIISOCYANATE
1,4-Benzenediisocyanate
1,4-diisocyanato-benzen
1,4-Diisocyanatobenzene
1,4-diisocyanato-Benzene
benzene,1,4-diisocyanato-
Isocyanic acid, p-phenylene ester
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1,4-Phenylene diisocyanate ISO 9001：2015 REACH
1,4-Phenylene disocyanate
1,4-Phenylenediisocyanate(PPDI)
P-PHENYLENE DIISOCYANATE
PPDI
104-49-4
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