Propargyl-PEG6-azide
- CAS No.
- 1198080-03-3
- Chemical Name:
- Propargyl-PEG6-azide
- Synonyms
- Propargyl-PEG6-N3;Azido-PEG6-propargyl;Propargyl-PEG6-azide;1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne;3,6,9,12,15,18-Hexaoxaheneicos-20-yne, 1-azido-;3-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne
- CBNumber:
- CB54849648
- Molecular Formula:
- C15H27N3O6
- Molecular Weight:
- 345.4
- MDL Number:
- MFCD31561110
- MOL File:
- 1198080-03-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Propargyl-PEG6-azide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | YXB08003 | 3-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne | 1198080-03-3 | 250mg | $1107.5 | 2026-06-05 | Buy |
| Biosynth | YXB08003 | 3-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne | 1198080-03-3 | 500mg | $1540 | 2026-06-05 | Buy |
| ChemScene | CS-0105434 | Propargyl-PEG6-N3 ≥95% | 1198080-03-3 | 100mg | $202 | 2026-06-04 | Buy |
| aablocks | AA019EEF | 1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne >98% | 1198080-03-3 | 10mg | $79 | 2026-05-29 | Buy |
| aablocks | AA019EEF | 1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne >98% | 1198080-03-3 | 25mg | $122 | 2026-05-29 | Buy |
Propargyl-PEG6-azide Chemical Properties,Uses,Production
Uses
Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biological Activity
Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Propargyl-PEG6-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG6-azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9948 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1977 | 58 |
| Changsha Bono New Materials Technology Co., Ltd. | 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
| Shanghai Minhan Pharmaceutical Technology Co., Ltd. | 17612188245 | 2816925681@qq.com | China | 8316 | 58 |
| Wuhan Topule | +86-02787215551 19945035818 | 2936752263@qq.com | China | 7985 | 58 |
View Lastest Price from Propargyl-PEG6-azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Propargyl-PEG6-N3
1198080-03-3
|
$39.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | Propargyl-PEG6-N3
1198080-03-3
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Propargyl-PEG6-N3
1198080-03-3
- $39.00
- TargetMol Chemicals Inc.
-
- Propargyl-PEG6-N3
1198080-03-3
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
