Azido-PEG1-CH2CO2-NHS
- CAS No.
- 1480545-09-2
- Chemical Name:
- Azido-PEG1-CH2CO2-NHS
- Synonyms
- N3-PEG1-CH2COO-NHS;Azido-PEG1-CH2COONHS;Azido-PEG1-CH2CO2-NHS;Azido-Peg1-CH2CO2-NH3;Azido-PEG1-CH2COO-NHS ester;Azido-PEG1-CH2COOH NHS Ester;2,5-dioxopyrrolidin-1-yl 2-(2-azidoethoxy)acetate
- CBNumber:
- CB23373563
- Molecular Formula:
- C8H10N4O5
- Molecular Weight:
- 242.19
- MDL Number:
- MFCD29067171
- MOL File:
- 1480545-09-2.mol
SAFETY
Risk and Safety Statements
| Signal word | Warning |
|---|---|
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P261-P304-P340-P302-P352-P362+P364-P305-P351-P338 |
Azido-PEG1-CH2CO2-NHS price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | bp-24047 | Azido-PEG1-CH2CO2-NHS 98% | 1480545-09-2 | 100MG | $280 | 2026-05-24 | Buy |
| BroadPharm | bp-24047 | Azido-PEG1-CH2CO2-NHS 98% | 1480545-09-2 | 250MG | $560 | 2026-05-24 | Buy |
| BroadPharm | bp-24047 | Azido-PEG1-CH2CO2-NHS 98% | 1480545-09-2 | 500MG | $840 | 2026-05-24 | Buy |
| BroadPharm | bp-24047 | Azido-PEG1-CH2CO2-NHS 98% | 1480545-09-2 | 1G | $1250 | 2026-05-24 | Buy |
| aablocks | AA01JOS5 | 2,5-Dioxo-1-pyrrolidinyl 2-(2-azidoethoxy)acetate 95% | 1480545-09-2 | 50mg | $113 | 2026-05-30 | Buy |
Azido-PEG1-CH2CO2-NHS Chemical Properties,Uses,Production
Description
Azido-PEG1-CH2CO2-NHS is a PEG linker containing azide and NHS ester moieties. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. The azide group can react with alkynes, BCN and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-CH2CO2-NHS Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG1-CH2CO2-NHS Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1977 | 58 |
| Xiamen Sinopeg Biotech Co., Ltd. | 400-9189898 17359873007 | sales@sinopeg.com | China | 1003 | 58 |
| Changsha Bono New Materials Technology Co., Ltd. | 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
| Shanghai Minhan Pharmaceutical Technology Co., Ltd. | 17612188245 | 2816925681@qq.com | China | 8316 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Shandong fen Boyu Biotechnology Co.,LTD | 13356310019 13356310019; | boyu2024@163.com | China | 3948 | 58 |
View Lastest Price from Azido-PEG1-CH2CO2-NHS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | N3-PEG1-CH2COO-NHS
1480545-09-2
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. |
-
- N3-PEG1-CH2COO-NHS
1480545-09-2
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
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