ChemicalBook >> CAS DataBase List >>1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione structure

CAS No.: 52450-18-7

Chemical Name:: 1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Synonyms: 3'-NH2-ddT;3'-Amino-2',3'-dideoxythymidine;1-((2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;3-AMT;Whi-02;Nsc620059;Aids000909;Ni 2-110-2;3'-NH?-ddT;Aids-000909

CBNumber:: CB5503076

Molecular Formula:: C10H15N3O4

Molecular Weight:: 241.24

MDL Number:: MFCD00038057

MOL File:: 52450-18-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:54:34

Request For Quotation

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Properties

Melting point	161-1620C
Density	1.360±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly, Heated), Methanol (Sparingly, Heated)
pka	9.55±0.10(Predicted)
form	Powder
color	Off-white to Yellow
Stability	Hygroscopic and Moisture Sensitive
InChI	InChI=1S/C10H15N3O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4,11H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1
InChIKey	ADVCGXWUUOVPPB-XLPZGREQSA-N
SMILES	OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1N
FDA UNII	7W21M0C25B

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	295121	3'-Amino-3'-deoxythymidine Asreported	52450-18-7	500mg	$305	2026-06-03	Buy
Usbiological	295121	3'-Amino-3'-deoxythymidine Asreported	52450-18-7	1g	$408	2026-06-03	Buy
Usbiological	295121	3'-Amino-3'-deoxythymidine Asreported	52450-18-7	2g	$526	2026-06-03	Buy
Usbiological	295121	3'-Amino-3'-deoxythymidine Asreported	52450-18-7	5g	$722	2026-06-03	Buy
Usbiological	295121	3'-Amino-3'-deoxythymidine Asreported	52450-18-7	10g	$950	2026-06-03	Buy

Product number	Packaging	Price	Buy
295121	500mg	$305	Buy
295121	1g	$408	Buy
295121	2g	$526	Buy
295121	5g	$722	Buy
295121	10g	$950	Buy

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical Properties, Uses, Production

Synthesis

Synthesis of 52450-18-7

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione can be prepared by reduction of 3'-azido-2',3'-dideoxythymidine under hydrogen and palladium on carbon, with a yield of 95%.

Chemical Properties

Off-White Solid

Uses

A metabolite of Zidovudine (3Azido-3deoxythymidine; AZT)

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Preparation Products And Raw materials

Raw materials

Preparation Products

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Suppliers

Global Suppliers ( 105)

Supplier	Tel	Email	Country	ProdList	Advantage
HeFei ShenShen Medical Technology Co.,Ltd	15375050680; 15375050680	gdz2.71828@163.com	China	31	58
Panaishen (Henan) Pharmaceutical Science and Technology Co. , Ltd.	0371-65325800 13700860222	haifeng.zhang@pannacean.com	China	1703	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Hongene Biotech Corporation	021-64757213	info@hongene.com	China	672	61
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
China DongFan Chemical Co.,LTD	86-0571-85151182		China	5681	66
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-83725681-603		China	4484	50
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12323	58
Nanjing Baifuli Technology Co., Ltd.	25-25-58740604 15951658055	sales@unisyn.cn	China	622	58

Supplier	Advantage
HeFei ShenShen Medical Technology Co.,Ltd	58
Panaishen (Henan) Pharmaceutical Science and Technology Co. , Ltd.	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Hongene Biotech Corporation	61
Chemsky（shanghai）International Co.,Ltd.	50
China DongFan Chemical Co.,LTD	66
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
Beijing HuaMeiHuLiBiological Chemical	58
Nanjing Baifuli Technology Co., Ltd.	58

View Latest Price from 1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-05	1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 52450-18-7	$1.00	1KG	98-99.9%	100kg	Career Henan Chemical Co

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
52450-18-7
$1.00
98-99.9%
Career Henan Chemical Co

52450-18-7 (1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione) Related Search:

2',3'-Dideoxythymidine Zidovudine 1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Fozivudine 3'-Azido-3'-deoxythymidine-5'-triphosphate

3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT 3'-AZIDO-2',3'-DIDEOXY-THYMIDINE-5'-MONOPHOSPHATE, SODIUM SALT 5'-O-Benzoyl-3'-azido-3'-deoxythymidine 3'-Azido 3'-deoxythymidine 5'-triphosphate, tetratriethylammonium salt 3'-Azido 3'-deoxythymidine, [methyl-3H]-

3'-Azido-3'-deoxythymidine-2-14C 5'-PHOSPHONATE-3'-AZIDO-3'-DEOXYTHYMIDINE CALCIUM SALT 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE, DIAMMONIUM SALT scriptene 3'-azido-3'-deoxythymidine 5'-diphosphate

3'-Azido 3'-deoxythymidine 5'-triphosphate, tetratriethylammonium salt, [methyl-3H]- Azt (methyl-13C) 3'-Azido 3'-deoxythymidine 5'-monophosphate, diammonium salt, [methyl-3H]-

1of4

Zidovudine Impurity 1 3-AMT Aids000909 Aids-000909 Ni 2-110-2 Nsc620059 Thymidine, 3'-amino-3'-deoxy- Whi-02 3''-AMINO-3''-DIDEOXYTHYMIDINE (AMT) 3’-aminothymidine 3'-AMINO-3'-DEOXY-D-THYMIDINE 3Deoxy-3aminothymidine 3''-AMINO-2'',3''-DIDEOXYTHYMIDINE(AMT) 3’-Amino-2’,3’-dideoxythymidine 3'' -AMINO-2'', 3''-DIDEOXYTHYMIDINE HPLC 98+% 1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione AMT/3′-Amino-2′,3-Dideoxythymidine 3'-NH?-ddT 1-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 3'-Amino-3'-deoxythymidine 3’-Amino-3’-deoxy thymidine, 3’-amino-ddT 1-((2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 3'-Amino-2',3'-dideoxythymidine 3'-NH2-ddT 3′-Amino-3′-deoxythymidine (ACI) 52450-18-7 52450-49-7 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Bases & Related Reagents Nucleotides