2-Heptyl-4-hydroxyquinoline N-oxide
- CAS No.
- 341-88-8
- Chemical Name:
- 2-Heptyl-4-hydroxyquinoline N-oxide
- Synonyms
- hqno;kf8940;C04284;Pyo II;Antibiotic KF-8940;HQNO, 10 mM in DMSO;NZPACTGCRWDXCJ-UHFFFAOYSA-N;2-heptyl-4-quinolino1-oxide;2-Heptylquinolin-4-ol 1-oxide;2-Heptyl-4-quinolinol 1-oxide
- CBNumber:
- CB5503571
- Molecular Formula:
- C16H21NO2
- Molecular Weight:
- 259.34
- MDL Number:
- MFCD00057295
- MOL File:
- 341-88-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 156-157° |
|---|---|
| Boiling point | 445.8±37.0 °C(Predicted) |
| Density | 1.09±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Soluble in DMSO (up to 8 mg/ml with warming), or in Ethanol (up to 13 mg/ml with warming). |
| pka | 1.07±0.40(Predicted) |
| form | White to off-white crystalline solid. |
| color | White |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| FDA UNII | 1FU5S5CG6A |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| RTECS | VC5890000 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 40mg/kg | |||||||||
| NFPA 704 |
|
2-Heptyl-4-hydroxyquinoline N-oxide price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15159 | HQNO ≥98% | 341-88-8 | 5mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 15159 | HQNO ≥98% | 341-88-8 | 10mg | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 15159 | HQNO ≥98% | 341-88-8 | 50mg | $479 | 2026-04-30 | Buy |
| ChemScene | CS-0104638 | HQNO 98.73% | 341-88-8 | 5mg | $69 | 2026-06-04 | Buy |
| ChemScene | CS-0104638 | HQNO 98.73% | 341-88-8 | 10mg | $108 | 2026-06-04 | Buy |
2-Heptyl-4-hydroxyquinoline N-oxide Chemical Properties, Uses, Production
Description
HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein. HQNO inhibits NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR).
Uses
HQNO is a streptomycin antagonist. A naturally occurring antagonist of dihydrostreptomycin.
Definition
ChEBI: 2-heptyl-4-hydroxyquinoline N-oxide is an inhibitor of the mitochondrial respiratory chain at cytochrome bc1 and of photosynthetic electron flow immediately before cytochrome b559. It is a monohydroxyquinoline and a quinoline N-oxide.
References
[1] Y NAKAYAMA. Inhibitor studies of a new antibiotic, korormicin, 2-n-heptyl-4-hydroxyquinoline N-oxide and Ag+ toward the Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus.[J]. Biological & pharmaceutical bulletin, 1999, 22 10: 1064-1067. DOI:10.1248/bpb.22.1064
2-Heptyl-4-hydroxyquinoline N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
2-Heptyl-4-hydroxyquinoline N-oxide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4860 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Rhawn Reagent | 400-400-1332688 18019345275 | huyue@rhawn.cn | China | 14942 | 58 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3307 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
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