Cyhalodiamide
- CAS No.
- 1262605-53-7
- Chemical Name:
- Cyhalodiamide
- Synonyms
- cyhalodiamide;Chlorfluorocyanilamide;1,2-Benzenedicarboxamide, 3-chloro-N2-(1-cyano-1-methylethyl)-N1-[2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-
- CBNumber:
- CB55486901
- Molecular Formula:
- C22H17ClF7N3O2
- Molecular Weight:
- 523.83
- MDL Number:
- MFCD34181163
- MOL File:
- 1262605-53-7.mol
| Melting point | 225-228oC |
|---|---|
| Boiling point | 469.1±45.0 °C(Predicted) |
| Density | 1.422±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 10.65±0.46(Predicted) |
| color | White to Off-White |
| FDA UNII | T8W4DN7ZFM |
Cyhalodiamide Chemical Properties,Uses,Production
Chemical Properties
Chlorfluazuron is white powder, melting point 215.6~218.8℃. Bulk density 0.198g/mL, stack density 0.338g/mL, water solubility 2.76×10-4g/L(20℃,pH 6). Solubility in solvent (g/L): ethyl acetate 19.875, n-hexane 4.0902×10-3, trichloromethane 2.3921, ethanol 9.4141, acetone 39.644, methanol 34.987.
Uses
Cyhalodiamide is a diamide insecticide and an agrochemical compound.
Definition
ChEBI: Cyhalodiamide is a dicarboxylic acid diamide obtained by formal condensation of the two carboxy groups of 2-chlorophthalic acid with the amino groups of 4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylaniline and 2-amino-2-methylpropanenitrile. It has a role as an insecticide and an agrochemical. It is a dicarboxylic acid diamide, an aromatic amide, an organofluorine compound, a member of monochlorobenzenes and a nitrile. It is functionally related to a phthalic acid.
Synthesis
Starting from 2-chlorophthalic anhydride, the 1-position amidation reaction is carried out with 4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylaniline in dichloromethane at 25°C for 6 hours, catalyzed by triethylamine, to obtain the monoamide intermediate; subsequently, this intermediate undergoes 2-position amidation with 2-amino-2-methylpropanenitrile in N,N-dimethylformamide (DMF), using triphosgene as the condensing agent, at 60°C for 12 hours; after the reaction, the reaction mixture is washed with water, concentrated under reduced pressure, and purified by recrystallization from an ethanol-water mixture (volume ratio 3:1), yielding Cyhalodiamide with a melting point of 216–218°C, a purity of 98.5%, and an overall yield of 78%.
Cyhalodiamide Preparation Products And Raw materials
Raw materials
Preparation Products
Cyhalodiamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LGC Science (Shanghai) Ltd. | 13564411808 | fan.yang@lgcgroup.com | China | 18217 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 9069 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39599 | 58 |
| Tanmo Quality Inspection Technology Co., Ltd. | 4008-099-669 | 23419001name@qq.com | CHINA | 6043 | 58 |
| Shanghai Titan Scientific Co.,Ltd | 15618770481 | yhx@titansci.com | China | 10000 | 58 |
| Shenzhen Aituo Trading Co., Ltd. | 13417589054 | CHINA | 352 | 58 |
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