JAK-IN-5
- CAS No.
- 2096999-92-5
- Chemical Name:
- JAK-IN-5
- Synonyms
- JAK-IN-5;JAK inhibitor 1;JAK-IN-5, 10 mM in DMSO;Inhibitor,JAK,Janus kinase,inhibit,JAKIN5,JAK IN 5;5-Ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl)phenol;5-ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl)phenol;Phenol, 5-ethyl-2-fluoro-4-[3-[4,5,6,7-tetrahydro-5-(1-methyl-4-piperidinyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-6-yl]-
- CBNumber:
- CB55540375
- Molecular Formula:
- C27H31FN6O
- Molecular Weight:
- 474.57
- MDL Number:
- MFCD31657397
- MOL File:
- 2096999-92-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
JAK-IN-5 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0041555 | JAK-IN-5 | 2096999-92-5 | 5mg | $487 | 2026-06-04 | Buy |
| ChemScene | CS-0041555 | JAK-IN-5 | 2096999-92-5 | 10mg | $867 | 2026-06-04 | Buy |
| ChemScene | CS-0041555 | JAK-IN-5 | 2096999-92-5 | 25mg | $1787 | 2026-06-04 | Buy |
| ChemScene | CS-0041555 | JAK-IN-5 | 2096999-92-5 | 50mg | $2762 | 2026-06-04 | Buy |
| aablocks | AA01JP1X | JAK-IN-5 98% | 2096999-92-5 | 1mg | $69 | 2026-05-30 | Buy |
JAK-IN-5 Chemical Properties, Uses, Production
Description
JAK inhibitor 1 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
Uses
JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
in vivo
JAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction[2].
JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung[2].
References
[1]. Paul R. Fatheree, et al. JAK Kinase Inhibitor Compounds for Treatment of Respiratory Disease. US20170121327A1
JAK-IN-5 Preparation Products And Raw materials
Raw materials
Preparation Products
JAK-IN-5 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 18108052721 | 2850505130@qq.com | China | 5037 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9867 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | +86-0513; 18051384581 | sales@chemhifuture.com | China | 3075 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2377 | 58 |
| Wuhan Shanhai Zhihe Biotechnology Co., Ltd. | 17771424646 | shoubull@126.com | China | 892 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
