| Company Name: |
Chengdu Peter-like Biotechnology Co., Ltd.
|
| Tel: |
18108052721 18108052721; |
| Email: |
2850505130@qq.com |
| Products Intro: |
Product Name:JAK-IN-5
CAS:2096999-92-5
Purity:>=98% Package:5mg;10mg;20mg;50mg;100mg;200mg
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JAK-IN-5 manufacturers
- JAK-IN-5
-
- $197.00
-
2026-05-11
- CAS:2096999-92-5
- Purity: 99.37%
- Supply Ability: 10g
- JAK-IN-5
-
- $197.00
-
2026-05-11
- CAS:2096999-92-5
- Purity: 99.37%
- Supply Ability: 10g
|
| | JAK-IN-5 Basic information |
| Product Name: | JAK-IN-5 | | Synonyms: | JAK-IN-5;Phenol, 5-ethyl-2-fluoro-4-[3-[4,5,6,7-tetrahydro-5-(1-methyl-4-piperidinyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-6-yl]-;Inhibitor,JAK,Janus kinase,inhibit,JAKIN5,JAK IN 5;5-ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl)phenol;5-Ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl)phenol;JAK inhibitor 1;JAK-IN-5, 10 mM in DMSO | | CAS: | 2096999-92-5 | | MF: | C27H31FN6O | | MW: | 474.57 | | EINECS: | | | Product Categories: | | | Mol File: | 2096999-92-5.mol |  |
| | JAK-IN-5 Chemical Properties |
| Boiling point | 734.5±60.0 °C(Predicted) | | density | 1.311±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 8.54±0.25(Predicted) |
| | JAK-IN-5 Usage And Synthesis |
| Description | JAK inhibitor 1 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283. | | Uses | JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283. | | in vivo | JAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction[2].
JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung[2].
| | References | [1]. Paul R. Fatheree, et al. JAK Kinase Inhibitor Compounds for Treatment of Respiratory Disease. US20170121327A1 |
| | JAK-IN-5 Preparation Products And Raw materials |
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