CHO-PEG8-azide
- CAS No.
- 2353410-13-4
- Chemical Name:
- CHO-PEG8-azide
- Synonyms
- CHO-PEG8-azide
- CBNumber:
- CB56199514
- Molecular Formula:
- C18H35N3O9
- Molecular Weight:
- 437.49
- MDL Number:
- MFCD31693703
- MOL File:
- 2353410-13-4.mol
CHO-PEG8-azide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA01JOSL | Ald-CH2-PEG8-azide ≥95% | 2353410-13-4 | 100mg | $520 | 2026-05-30 | Buy |
| aablocks | AA01JOSL | Ald-CH2-PEG8-azide ≥95% | 2353410-13-4 | 250mg | $983 | 2026-05-30 | Buy |
| aablocks | AA01JOSL | Ald-CH2-PEG8-azide ≥95% | 2353410-13-4 | 500mg | $1420 | 2026-05-30 | Buy |
| BroadPharm | BP-24116 | Ald-CH2-PEG8-azide 98% | 2353410-13-4 | 100mg | $380 | 2021-12-16 | Buy |
| BroadPharm | BP-24116 | Ald-CH2-PEG8-azide 98% | 2353410-13-4 | 250mg | $750 | 2021-12-16 | Buy |
CHO-PEG8-azide Chemical Properties, Uses, Production
Description
Ald-CH2-PEG8-azide is a monodisperse PEG crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. PEG8 spacer increases solubility in aqueous media. aldehyde can be used in PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage.
Uses
Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Ald-CH2-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
CHO-PEG8-azide Preparation Products And Raw materials
Raw materials
Preparation Products
CHO-PEG8-azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50068 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
