Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Structure
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol structure
CAS No.
214360-76-6
Chemical Name:
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
Synonyms
132347;522562_Aldrich;Pinacol cyclic ester;2-DIOXABOROLAN-2-YL)PHENOL;3-Hydroxyphenylboronic acid pinacol este;3-HYDROXYBENZENEBORONIC ACID PINACOL ESTER;3-HYDROXYPHENYLBORONIC ACID, PINACOL ESTER;3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol;3-Hydroxybenzeneboronic acid, pinacol ester 98%;3-HYDROXYPHENYLBORONIC ACID, PINACOL CYCLIC ESTER
CBNumber:
CB5667617
Molecular Formula:
C12H17BO3
Molecular Weight:
220.07
MDL Number:
MFCD02093755
MOL File:
214360-76-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:38
Request For Quotation

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Properties

Melting point 94-98 °C(lit.)
Boiling point 343.6±25.0 °C(Predicted)
Density 1.08±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
Water Solubility Insoluble in water
pka 10.01±0.10(Predicted)
form Crystalline Powder
color Light brown
InChI InChI=1S/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-6-5-7-10(14)8-9/h5-8,14H,1-4H3
InChIKey MUKIFYQKIZOYKT-UHFFFAOYSA-N
SMILES C1(O)=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1
CAS DataBase Reference 214360-76-6(CAS DataBase Reference)
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
TSCA  No
HazardClass  IRRITANT
HS Code  29319090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 522562 3-Hydroxyphenylboronic acid pinacol ester 97% 214360-76-6 5g $282 2026-04-30 Buy
Sigma-Aldrich 522562 3-Hydroxyphenylboronic acid pinacol ester 97% 214360-76-6 1g $85.4 2023-06-20 Buy
TCI Chemical T1953 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol >98.0%(GC) 214360-76-6 1g $55 2026-04-30 Buy
TCI Chemical T1953 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol >98.0%(GC) 214360-76-6 5g $186 2026-04-30 Buy
Strem Chemicals 05-1043 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, min. 97% min.97% 214360-76-6 1g $109 2026-04-30 Buy
Product number Packaging Price Buy
522562 5g $282 Buy
522562 1g $85.4 Buy
T1953 1g $55 Buy
T1953 5g $186 Buy
05-1043 1g $109 Buy

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Chemical Properties, Uses, Production

Chemical Properties

light brown crystalline powder

Uses

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

Pinacol

76-09-5

3-Hydroxyphenylboronic acid

87199-18-6

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL

214360-76-6

The general procedure for the synthesis of 3-hydroxyphenylboronic acid pinacol ester from pinacol and 3-hydroxyphenylboronic acid was as follows: 3-hydroxyphenylboronic acid (10.0 g, 72.46 mmol, 1.0 eq.) and dichloromethane (300 mL) were added to a 500 mL three-necked flask with pinacol (10.0 g, 84.60 mmol, 1.2 eq.) under stirring. Subsequently, the reaction mixture was stirred continuously for 48 hours at room temperature. Upon completion of the reaction, the reaction solution was poured into water (400 mL) and transferred to a partition funnel for separation. After separation of the organic phase, the aqueous phase was extracted twice with dichloromethane (400 mL). All organic phases were combined, dried with anhydrous sodium sulfate and filtered to remove the desiccant. The crude product was purified by column chromatography (using 200-300 mesh silica gel and a solvent mixture of dichloromethane/methanol as eluent, 100:1, v/v), resulting in 15.0 g of white solid product in 94% yield and 97% purity.

References

[1] Patent: CN107188901, 2017, A. Location in patent: Paragraph 0035; 0036
[2] Organic Letters, 2010, vol. 12, # 23, p. 5474 - 5477

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Preparation Products And Raw materials

Raw materials

Pinacol 3-Hydroxyphenylboronic acid

Preparation Products

2,4-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol N-Isopropyl-2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy)Acetamide

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Suppliers

Global Suppliers ( 207)
Supplier Tel Email Country ProdList Advantage
Hangzhou SuGuan Chemical Technology Co., Ltd. 15958048562 2032153781@qq.com China 463 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Supplier Advantage
Hangzhou SuGuan Chemical Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
PharmaBlock Sciences (Nanjing),Inc. 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
Ark Pharm, Inc. 56
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64

View Latest Price from 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL pictures 2021-07-13 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
214360-76-6
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL pictures 2021-07-10 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
214360-76-6
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL pictures 2019-07-06 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
214360-76-6
 $2.00 1KG 99% Career Henan Chemical Co

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Spectrum

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL(214360-76-6)1HNMR3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL(214360-76-6)1HNMR3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL(214360-76-6)IR

214360-76-6 (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol) Related Search:

3-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid pinacol ester 4-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-1,4-benzoxazine 3-Hydroxyphenylboronic acid 4-Hydroxyphenylboronic acid pinacol ester 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
3,4-Dimethoxyphenylboronic acid, pinacol ester 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-Acetoxy-4-methoxyphenylboronic acid, pinacol ester 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl acetate 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2-(3-Benzyloxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3-Methoxyphenylboronic Acid Pinacol Ester 1,4-Benzodioxane-6-boronic acid, pinacol ester 3-(Trifluoromethoxy)phenylboronic acid, pinacol ester
3-Benzyloxy-4-methoxyboronic acid, pinacol ester tert-Butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl carbonate 2-[3-([1,3]Dioxolan-2-ylmethoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

1of4

2-(3-Hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3-Hydroxyphenylboronic Acid Pinacol Ester 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol 3-Hydroxyphenylboronic Acid 522562_Aldrich 2-(3-HYDROXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 3-HYDROXYBENZENEBORONIC ACID PINACOL ESTER 3-HYDROXYPHENYLBORONIC ACID, PINACOL CYCLIC ESTER 3-HYDROXYPHENYLBORONIC ACID, PINACOL ESTER 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol,min.97% 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL, MIN. 97% 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, 3-Hydroxyphenylboronic acid, Pinacol cyclic ester 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol,97% 3-Hydroxyphenylboronic acid pinacol este Pinacol cyclic ester 2-DIOXABOROLAN-2-YL)PHENOL 3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenol (3-hydroxy-2,3-dimethylbutan-2-yl)oxy-(3-hydroxyphenyl)borinic acid 3-Hydroxybenzeneboronic acid, pinacol ester 98% 132347 Phenol, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 214360-76-6 Boronic Acids Esters B (Classes of Boron Compounds) Organometallic Reagents Aryl Boronate Esters Boronic Acids and Derivatives BORONIC ACID Aryl Boronate Esters Boronate Esters Boronic Acids and Derivatives Chemical Synthesis Organometallic Reagents Isoxazoles ,Oxazoles organic or inorganic borate B (Classes of Boron Compounds) Boronic Acids Esters Boronic acids