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4-Chloro-2-(trifluoromethyl)phenyl isocyanate

4-Chloro-2-(trifluoromethyl)phenyl isocyanate Structure
4-Chloro-2-(trifluoromethyl)phenyl isocyanate structure
CAS No.
16588-69-5
Chemical Name:
4-Chloro-2-(trifluoromethyl)phenyl isocyanate
Synonyms
TIMTEC-BB SBB006655;4-Chloro-2-(trifluoromethyl)phenyl isocyanate;4-Chloro-2-(trifluoromethyl)phenylisocyanate97%;4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene;4-Chloro-2-(trifluoromethyl)phenyl isocyanate,98%;4-Chloro-2-(trifluoromethyl)phenyl isocyanate 97%;Benzene, 4-chloro-1-isocyanato-2-(trifluoromethyl)-
CBNumber:
CB5674785
Molecular Formula:
C8H3ClF3NO
Molecular Weight:
221.56
MDL Number:
MFCD00013873
MOL File:
16588-69-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:38
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4-Chloro-2-(trifluoromethyl)phenyl isocyanate Properties

Boiling point 64-64.5 °C0.5 mm Hg(lit.)
Density 1.467 g/mL at 25 °C(lit.)
refractive index n20/D 1.501(lit.)
Flash point 202 °F
form liquid
color clear colourless
Sensitive Moisture Sensitive
BRN 2214336
CAS DataBase Reference 16588-69-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H334-H335
Precautionary statements  P261-P280a-P284-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  7-26-27-37/39-45-36/37/39
RIDADR  UN 2206 6.1/PG 3
WGK Germany  3
Hazard Note  Harmful
HazardClass  6.1
PackingGroup  III
HS Code  29291090
NFPA 704
1
2 0

4-Chloro-2-(trifluoromethyl)phenyl isocyanate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T341584 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE AldrichCPR 16588-69-5 1 unit $197 2026-04-30 Buy
Sigma-Aldrich T341584 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE Aldrich 16588-69-5 1g $179 2024-03-01 Buy
Usbiological 267669 4-Chloro-2-(trifluoromethyl)phenyl isocyanate Asreported 16588-69-5 1g $319 2026-06-03 Buy
Usbiological 267669 4-Chloro-2-(trifluoromethyl)phenyl isocyanate Asreported 16588-69-5 2g $432 2026-06-03 Buy
Usbiological 267669 4-Chloro-2-(trifluoromethyl)phenyl isocyanate Asreported 16588-69-5 5g $602 2026-06-03 Buy
Product number Packaging Price Buy
T341584 1 unit $197 Buy
T341584 1g $179 Buy
267669 1g $319 Buy
267669 2g $432 Buy
267669 5g $602 Buy

4-Chloro-2-(trifluoromethyl)phenyl isocyanate Chemical Properties,Uses,Production

Chemical Properties

clear colorless liquid

Uses

4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene is a reagent used in the synthesis of benzothiazole compounds targeting chemokine receptor 2 which ma be used in the treatment of antiinflammatory diseases.

4-Chloro-2-(trifluoromethyl)phenyl isocyanate synthesis

32315-10-9
445-03-4
16588-69-5
Synthesis of 4-Chloro-2-(trifluoromethyl)phenyl isocyanate from Triphosgene and 2-Amino-5-chlorobenzotrifluoride

4-Chloro-2-(trifluoromethyl)phenyl isocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

4-Chloro-2-(trifluoromethyl)phenyl isocyanate Suppliers

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Beijing FYF Chemicals Co., Ltd 010-57903446 15869909019 168931144@qq.com China 2876 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
Energy Chemical 61
Capot Chemical Co., Ltd 66
Nanjing Norris-Pharm Technology Co., Ltd 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Chengdu HuaXia Chemical Reagent Co. Ltd 58
Beijing FYF Chemicals Co., Ltd 58

16588-69-5(4-Chloro-2-(trifluoromethyl)phenyl isocyanate)Related Search:

2-Chloro-4-(trifluoromethyl)phenyl isocyanate 2-Chloro-6-(trifluoromethyl)phenyl isocyanate 4-Chloro-2-methylphenyl isocyanate 4-Chloro-2-(trifluoromethyl)phenyl isocyanate 2-Chloro-5-(trifluoromethyl)phenyl isocyanate
2-(Trifluoromethyl)phenyl isocyanate 4-Chloro-3-(trifluoromethyl)phenyl isocyanate 4-Chloro-3-(trifluoromethyl)phenyl isocyanate （Sorafenib Intermediate） 2-Aminobenzotrifluoride 3-Chlorobenzotrifluoride
2-Methylphenyl isocyanate 2-Amino-5-chlorobenzotrifluoride 4-Chlorophenyl isocyanate

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TIMTEC-BB SBB006655 4-Chloro-2-(trifluoromethyl)phenyl isocyanate 97% 4-Chloro-2-(trifluoromethyl)phenylisocyanate97% 4-Chloro-2-(trifluoromethyl)phenyl isocyanate,98% 4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene Benzene, 4-chloro-1-isocyanato-2-(trifluoromethyl)- 4-Chloro-2-(trifluoromethyl)phenyl isocyanate 16588-69-5 C8H3CIF3NO Organic Building Blocks Nitrogen Compounds Isocyanates ARYL ISOCYANATE Building Blocks Phenyl isocyanate&Phenyl isothiocyanate