DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)
- CAS No.
- 85272-30-6
- Chemical Name:
- DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE)
- Synonyms
- DK412;diisopropylbis(trifluoromethanesulfonyl)silane;DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE);Diisopropylsilylenebis(trifluoromethanesulfonate);Diisopropylsilanediyl bis(trifluoromethanesulfonate);TRIFLUOROMETHANESULFONIC ACID DIISOPROPYLSILYLENE ESTER;DIISOPROPYLSILYL BIS(TRIFLUOROMETHANE-SU LFONATE), TECH.;Bis(trifluoromethanesulfonic acid)diisopropylsilanediyl ester;Bis(1-methylethyl)[[(trifluoromethyl)sulfonyl]oxy]silyl triflate;Methanesulfonic acid, trifluoro-, bis(1-methylethyl)silylene ester
- CBNumber:
- CB5678556
- Molecular Formula:
- C8H14F6O6S2Si
- Molecular Weight:
- 412.4
- MDL Number:
- MFCD00043111
- MOL File:
- 85272-30-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Diisopropylsilyl bis(trifluoromethanesulfonate) 96% | 375942 | 5g | $127 |
| Diisopropylsilyl bis(trifluoromethanesulfonate) 96% | 375942 | 25g | $559 |
| Diisopropylsilyl Bis(Trifluoromethanesulfonate) | FD90402 | 5g | $900 |
| Diisopropylsilyl Bis(Trifluoromethanesulfonate) | FD90402 | 2g | $900 |
| Diisopropylsilyl Bis(Trifluoromethanesulfonate) | FD90402 | 1g | $900 |
| More product size | |||
| Boiling point | 85-86 °C2 mm Hg(lit.) |
|---|---|
| Density | 1.396 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| form | liquid |
| Specific Gravity | 1.396 |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 3567500 |
| InChI | 1S/C8H14F6O6S2Si/c1-5(2)23(6(3)4,19-21(15,16)7(9,10)11)20-22(17,18)8(12,13)14/h5-6H,1-4H3 |
| InChIKey | BHZPNBNSRVSTBW-UHFFFAOYSA-N |
| SMILES | CC(C)[Si](OS(=O)(=O)C(F)(F)F)(OS(=O)(=O)C(F)(F)F)C(C)C |
| UNSPSC Code | 12352001 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 |
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard Codes | C |
| Risk Statements | 34-37 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| F | 10-21 |
| HazardClass | 8 |
| PackingGroup | III |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Skin Corr. 1B |
DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 375942 | Diisopropylsilyl bis(trifluoromethanesulfonate) 96% | 85272-30-6 | 5g | $127 | 2025-07-31 | Buy |
| Sigma-Aldrich | 375942 | Diisopropylsilyl bis(trifluoromethanesulfonate) 96% | 85272-30-6 | 25g | $559 | 2023-06-20 | Buy |
| Biosynth | FD90402 | Diisopropylsilyl Bis(Trifluoromethanesulfonate) | 85272-30-6 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | FD90402 | Diisopropylsilyl Bis(Trifluoromethanesulfonate) | 85272-30-6 | 2g | $900 | 2026-06-04 | Buy |
| Biosynth | FD90402 | Diisopropylsilyl Bis(Trifluoromethanesulfonate) | 85272-30-6 | 1g | $900 | 2026-06-04 | Buy |
DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Chemical Properties,Uses,Production
Physical properties
bp 85–86°C/2mmHg;d 1.396 g cm3; fp 110°C.
Uses
Diisopropylsilyl
bis(trifluoromethanesulfonate) has more recently been
used to prepare diisopropylsilyl-linked oligonucleotide analogs.
Silylation of 5'-O-(dimethoxytrityl)-2'-deoxynucleosides using
diisopropylsilyl bis(trifluoromethanesulfonate) and the hindered
base 2,6-di-t-butyl-4-methylpyridine (Dtbp) provided quantitative
yield of 3'-O-diisopropylsilanols (eq 2). Hence, silylation
of 5'-O-(dimethoxytrityl)thymidine, N6-benzoyl-2'-deoxy-5'-O-
(dimethoxytrityl)adenosine, N4-benzoyl-2'-deoxy-5'-O-(dimethoxytrityl)
cytidine, and N2-isobutyryl-2'-deoxy-5'-O-(dimethoxytrityl)
guanosine gave the desired products 5a–d in excellent
yields.
Coupling of products 5a–d with unprotected thymidine
resulted in formation of 3',5'-linked dinucleosides 6a–d selectively,
and the dimer 7 from reaction with secondary hydroxyl
group of thymidine was not observed (eq 3). Subsequent silylation
and coupling with another molecule of thymidine gave 3,5-
linked trinucleoside 8 in 76% yield (eq 4). A tetrathymidylate oligomer was prepared by 3'-O-silylation of 8 followed by
coupling with thymidine. Although no self-condensation was
observed, only 30% of the product 9 was obtained after purification
by preparative HPLC.
Preparation
conveniently prepared by the slow addition of 2 equiv of trifluoromethanesulfonic acid to a stirring mixture of chlorodiisopropylsilane, followed by direct distillation of the product from the reaction flask to yield the product as a pale yellow oil.
storage
DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) should be stored in the refrigerator under an inert atmosphere of argon or nitrogen. Special care should be used when handling since diisopropysilyl bis(trifluoromethanesulfonate) has been classified as a corrosive.
DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14035 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Shanghai Zhuangming Biopharma Co., Ltd. | inquiry@zmsilane.com | China | 725 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18934348241 | sales4.gd@hwrkchemical.com | China | 14060 | 55 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Xuzhou ZhuoYun New Material Technology Co., Ltd. | 0516-0516 13776763863 | zhangqinli.ok@163.com | China | 1305 | 58 |
View Lastest Price from DIISOPROPYLSILYL BIS(TRIFLUOROMETHANESULFONATE) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | diisopropylbis(trifluoromethanesulfonyl)silane
85272-30-6
|
$1.00 | 1KG | Min98% | Career Henan Chemical Co |
-
- diisopropylbis(trifluoromethanesulfonyl)silane
85272-30-6
- $1.00
- Min98%
- Career Henan Chemical Co
