PROTEIN L
- CAS No.
- Chemical Name:
- PROTEIN L
- Synonyms
- PROTEIN L;Protein L from Peptostreptococcus magnus
- CBNumber:
- CB5681020
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01635653
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Protein L from Peptostreptococcus magnus >95% (SDS-PAGE), recombinant, expressed in E. coli, essentially salt-free, lyophilized pow | P3101 | 5 mg | $640 |
| Protein L from Peptostreptococcus magnus | P3101 | 5mg | $620 |
| PROTEIN L 95.00% | PRO0000576 | 5MG | $500.57 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
PROTEIN L price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P3101 | Protein L from Peptostreptococcus magnus >95% (SDS-PAGE), recombinant, expressed in E. coli, essentially salt-free, lyophilized pow | 5 mg | $640 | 2025-07-31 | Buy | |
| Sigma-Aldrich | P3101 | Protein L from Peptostreptococcus magnus | 5mg | $620 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | PRO0000576 | PROTEIN L 95.00% | 5MG | $500.57 | 2021-12-16 | Buy |
PROTEIN L Chemical Properties,Uses,Production
Uses
Protein L from Peptostreptococcus magnus is suitable for use in indirect ELISA (1:100,000). This product may also be used for immunohistochemistry in rat kidney sections .
General Description
Protein L is an immunoglobulin light chain-binding protein. It is expressed by a few anaerobic bacterial species, such as Peptostreptococcus magnus.
Biochem/physiol Actions
Protein L from Peptostreptococcus magnus binds immunoglobulins (Ig) primarily through kappa light chain interactions without interfering with the antigen binding sites of Ig′s. This means that Protein L binds to a wider range of Ig classes and subclasses from a variety of species than any other commercially available Ig binding protein. It contains four Ig binding domains (B-domains). It may be used for the purification of IgG, IgM, IgA, IgE and IgD containing κ light chains and for the purification of Fab and scFv fragments containing κ light chains. It may be conjugated to a solid support for affinity purification or conjugated to marker molecules for use in detection. Protein L does not bind to bovine, sheep or goat immunoglobulins. For this reason it may be used for the purification of monoclonal antibodies from media supplemented with bovine serum albumin or fetal calf serum. It can also be used to purify human or mouse antibodies from goat, bovine or sheep proteins. A comprehensive list of binding properties is found in the product data sheet.
Description
Protein-L Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 365 amino acids and having a molecular mass of 40.5 kDa but it migrates with an apparent molecular mass of 45 kDa in SDS-PAGE.The Protein-L is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
The recombinant Protein L is genetically engineered protein and holds 5 IgG-binding regions of protein L and it has the exclusive capability to bind through kappa light chain interactions without interfering with the antibody’s antigen-binding site. Cell wall binding region, cell membrane binding region and albumin binding region were removed to ensure the highest specific IgG binding. The recombinant Protein L is perfect for purification of polyclonal or monoclonal IgG antibodies and it binds to human, mouse, rat and pig IgG.
PROTEIN L Preparation Products And Raw materials
Raw materials
Preparation Products
PROTEIN L Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9865 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1495 | 58 |
| Enzo Biochem Inc | Enzo Biochem Inc. 13797054060 | Enzoname@qq.com | China | 6174 | 58 |
| Beijing Biosynthesis Biotechnology Co Ltd | 400-9019800 | sales@bioss.com.cn | China | 6102 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 6215 | 58 |
| ProSpec Tany TechnoGene Ltd | 972-8947-1175 | info@prospecbio.com | China | 6874 | 58 |
| Guangzhou Kangkaixin Biotechnology Co., Ltd. | 13760798286 | CHINA | 6788 | 58 | |
| Guangzhou Linyun Biotechnology Co., Ltd | 18024570953 | CHINA | 961 | 58 |
