ChemicalBook >> CAS DataBase List >>1-(2-Chloroethyl)azepane hydrochloride
1-(2-Chloroethyl)azepane hydrochloride
- CAS No.
- 26487-67-2
- Chemical Name:
- 1-(2-Chloroethyl)azepane hydrochloride
- Synonyms
- 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE;Bazedoxifeno int;BAZEDOXIFENE int1;1-(2-Chloro ethyl) azepane HCl;2-CHLOROETHYLHEXAMETHYLENE IMINE HCL;2-ChloroethylhexamethyleneImineHcl99%;1-(2-Chloroethyl)azepane hydrochloride;N-(2-Chloroethyl)azepane hydrochloride.;2-Chloroethylhexamethylene Imine Hcl 99%;azepin-1-yl)ethyl chloride hydrochloride
- CBNumber:
- CB5693188
- Molecular Formula:
- C8H17Cl2N
- Molecular Weight:
- 198.13
- MDL Number:
- MFCD00012842
- MOL File:
- 26487-67-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-23 14:48:42
| Product description | Number | Pack Size | Price |
| 1-(2-Chloroethyl)-1H-hexahydroazepine Hydrochloride >98.0%(T) | C2379 | 5g | $18 |
| 1-(2-Chloroethyl)-1H-hexahydroazepine Hydrochloride >98.0%(T) | C2379 | 25g | $49 |
| 1-(2-Chloroethyl)azepane hydrochloride 98% | OR0989 | 1g | $21 |
| 1-(2-Chloroethyl)azepane hydrochloride 98% | OR0989 | 5g | $55 |
| 1-(2-Chloroethyl)azepane hydrochloride 98% | OR0989 | 25g | $98 |
| More product size | |||
| Melting point | 208-210°C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| color | White to Almost white |
| Sensitive | Hygroscopic |
| BRN | 3680388 |
| InChI | InChI=1S/C8H16ClN.ClH/c9-5-8-10-6-3-1-2-4-7-10;/h1-8H2;1H |
| InChIKey | ZQDSOUPBYJIPNM-UHFFFAOYSA-N |
| SMILES | N1(CCCl)CCCCCC1.Cl |
| CAS DataBase Reference | 26487-67-2(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H332-H315-H319-H302-H331-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/22-36/37-39-52-22-36/38-20 | |||||||||
| Safety Statements | 22-26-36/37/39-51-20/21 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| RTECS | CM3185000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications | Acute Tox. 3 Oral Aquatic Chronic 3 |
|||||||||
| Toxicity | mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00612, | |||||||||
| NFPA 704 |
|
1-(2-Chloroethyl)azepane hydrochloride price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2379 | 1-(2-Chloroethyl)-1H-hexahydroazepine Hydrochloride >98.0%(T) | 26487-67-2 | 5g | $18 | 2026-04-30 | Buy |
| TCI Chemical | C2379 | 1-(2-Chloroethyl)-1H-hexahydroazepine Hydrochloride >98.0%(T) | 26487-67-2 | 25g | $49 | 2026-04-30 | Buy |
| Apolloscientific | OR0989 | 1-(2-Chloroethyl)azepane hydrochloride 98% | 26487-67-2 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR0989 | 1-(2-Chloroethyl)azepane hydrochloride 98% | 26487-67-2 | 5g | $55 | 2026-06-04 | Buy |
| Apolloscientific | OR0989 | 1-(2-Chloroethyl)azepane hydrochloride 98% | 26487-67-2 | 25g | $98 | 2026-06-04 | Buy |
1-(2-Chloroethyl)azepane hydrochloride Chemical Properties,Uses,Production
Uses
1-(2-Chloroethyl)azepane hydrochloride is a key intermediate of bazedoxifene and setastine.
Synthesis
2205-31-4
26487-67-2
General procedure for the synthesis of 2-(cyclohexylimino)ethyl chloride hydrochloride from 1-(2-chloroethyl)azepane: 165.9 g of isopropanol was added to the reaction system, and dry hydrogen chloride gas was slowly vented under stirring until the pH of the reaction system was ≤2.5 when the venting was stopped. The reaction mixture was heated to a maximum of 80 °C with continuous stirring for 30 minutes. Subsequently, 2.8 g of activated carbon was added and stirring was continued for 30 minutes. Upon completion of the reaction, thermal filtration was performed to remove the activated carbon. The filtrate was cooled to 0-5°C and left to crystallize for 8 hours. Upon completion of crystallization, the solid product was collected by filtration and dried to give 53.1 g of N-(2-chloroethyl)hexamethyleneimine hydrochloride in 84.5% yield. The purity of the product N-(2-chloroethyl)hexamethyleneimine hydrochloride was tested to be 98.6%.
References
[1] Patent: CN104693144, 2016, B. Location in patent: Paragraph 0030; 0033
1-(2-Chloroethyl)azepane hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 205)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao Yonghefeng Economic and Trade Co., Ltd. | +86-13375559818 | cfy69@163.com | China | 195 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-15790943001 | crystal@sorawin.cn | China | 419 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 955 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
View Lastest Price from 1-(2-Chloroethyl)azepane hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-23 | 1-(2-Chloroethyl)azepane hydrochloride
26487-67-2
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-08-20 | 1-(2-Chloroethyl)azepane hydrochloride
26487-67-2
|
1kg | 99.99% | 20 tons | Chongqing Soarwin Technology Co., Ltd | ||
 |
2023-08-16 | 1-(2-Chloroethyl)azepane hydrochloride (1:1)
26487-67-2
|
$20.00 | 1KG | >99% | 50000kg/Month | Weijer International Trade (Hebei) Co., Ltd |
-
- 1-(2-Chloroethyl)azepane hydrochloride
26487-67-2
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 1-(2-Chloroethyl)azepane hydrochloride
26487-67-2
- 99.99%
- Chongqing Soarwin Technology Co., Ltd
-
- 1-(2-Chloroethyl)azepane hydrochloride (1:1)
26487-67-2
- $20.00
- >99%
- Weijer International Trade (Hebei) Co., Ltd
26487-67-2(1-(2-Chloroethyl)azepane hydrochloride)Related Search:
1-(2-CHLOROETHYL) HEXAMETHYLENIMINE
ACETIC ACID 2,2-DICHLORO-1-(2-OXO-AZEPAN-1-YL)-ETHYL ESTER
2-Chloroethyldimethylamine
2-Dimethylaminoethyl chloride hydrochloride
1-(2,2-DICHLORO-1-HYDROXY-ETHYL)-AZEPAN-2-ONE
1of3
1-(2-chloroethyl)-hexahydro-1h-azepinehydrochloride
hexahydro-1-(2-chloroethyl)-1h-azepinhydrochloride
2-CHLOROETHYLHEXAMETHYLENE IMINE HCL
2-CHLOROETHYLHEXAMETHYLENEMINE HYDROCHLORIDE
2-ChloroethylhexamethyleneImineHcl99%
2-Chloroethylhexamethylene Imine Hcl 99%
N-(2-CHLOROETHYL)HEXAHYDRO-1H-AZEPINE HYDROCHLORIDE
N-(2-chloroethyl)perhydroazepine hydrochloride
1-(2-Chloroethyl)azepane hydrochloride
N-(2-Chloroethyl)azepane hydrochloride.
1-(2-Chloroethyl)azepane hydrochloride 98%
2-(hexamethyleneimino)ethyl chloride monohydrochloride
1-(2-Chloroethyl)-1H-hexahydroazepine Hydrochloride
2-(Hexamethyleneimino)ethyl chloride hydrochloride,98%
2-(Hexamethyleneimino)ethyl chloride hydrochloride, 1-(2-Chloroethyl)hexahydro-1H-azepine hydrochloride, 1-(2-Chloroethyl)homopiperidine hydrochloride, 1-(Azepan-1-yl)-2-chloroethane hydrochloride
1-(2-Chloroethyl)hexamethyleneimine Hydrochloride
azepin-1-yl)ethyl chloride hydrochloride
2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HCL
1-(2-Chloroethyl)azepanehydrochloride98%
2-Chloroethyl hexamethylene Imine hydrochloride
BAZEDOXIFENE int1
Bazedoxifeno int
2-chloro-N-(6-chlorohexyl)ethanimine hydrochloride
1-(2-Chloroethyl)-1H-hexahydroazepineHydrochloride>
1H-Azepine, 1-(2-chloroethyl)hexahydro-, hydrochloride (1:1)
1-(2-Chloroethyl)azepane hydrochloride (1:1)
Hexamethylenimineethylchloride hydrochloride
1-(2-Chloroethyl)azepane hydrochloride 26487-67-2
1-(2-chloroethyl)hexahydro-1H-Azepine hydrochloride (1:1)
Hexahydro-1-(2-chloroethyl)-1H-azepine hydrochloride
1-(2-Chloro ethyl) azepane HCl
2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE
26487-67-2
C8H17NCl2
C8H16ClNClH
C8H17Cl2N
Miscellaneous
