4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
- CAS No.
- 34785-11-0
- Chemical Name:
- 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
- Synonyms
- NSC 4344;AKOS BBS-00000364;IFLAB-BB F2124-0013;Sotuletinib Impurity5;4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID;3-Quinolinecarboxylic acid, 4-hydroxy-;4-hydroxyquinolinone-3-carboxylic acid;4-Hydroxyquinoline-3-carboxylic acid 97%;Ivacaftor impurities8（Kynurenic Acid Impurity 4）;4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ISO 9001：2015 REACH
- CBNumber:
- CB5697111
- Molecular Formula:
- C10H7NO3
- Molecular Weight:
- 189.17
- MDL Number:
- MFCD00598887
- MOL File:
- 34785-11-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Hydroxyquinoline-3-carboxylic acid 97% | 750360 | 5g | $72.5 |
| 4-Hydroxyquinoline-3-carboxylic acid Asreported | 280140 | 1g | $366 |
| 4-Hydroxyquinoline-3-carboxylic acid Asreported | 280140 | 2g | $508 |
| 4-Hydroxyquinoline-3-carboxylic acid Asreported | 280140 | 5g | $912 |
| 4-Hydroxyquinoline-3-carboxylic acid Asreported | 280140 | 10g | $1297 |
| More product size | |||
| Melting point | 268-273°C |
|---|---|
| Boiling point | 384.7±32.0 °C(Predicted) |
| Density | 1.480 |
| storage temp. | 2-8°C, stored under nitrogen |
| pka | 0.81±0.30(Predicted) |
| form | solid |
| Appearance | Off-white to light brown Solid |
| InChI | InChI=1S/C10H7NO3/c12-9-6-3-1-2-4-8(6)11-5-7(9)10(13)14/h1-5H,(H,11,12)(H,13,14) |
| InChIKey | ILNJBIQQAIIMEY-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)C(O)=C(C(O)=O)C=1 |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| HS Code | 2933499090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 750360 | 4-Hydroxyquinoline-3-carboxylic acid 97% | 34785-11-0 | 5g | $72.5 | 2025-07-31 | Buy |
| Usbiological | 280140 | 4-Hydroxyquinoline-3-carboxylic acid Asreported | 34785-11-0 | 1g | $366 | 2026-06-03 | Buy |
| Usbiological | 280140 | 4-Hydroxyquinoline-3-carboxylic acid Asreported | 34785-11-0 | 2g | $508 | 2026-06-03 | Buy |
| Usbiological | 280140 | 4-Hydroxyquinoline-3-carboxylic acid Asreported | 34785-11-0 | 5g | $912 | 2026-06-03 | Buy |
| Usbiological | 280140 | 4-Hydroxyquinoline-3-carboxylic acid Asreported | 34785-11-0 | 10g | $1297 | 2026-06-03 | Buy |
4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID Chemical Properties,Uses,Production
Synthesis
26892-90-0
34785-11-0
The general procedure for the synthesis of 4-hydroxyquinoline-3-carboxylic acid from ethyl 4-hydroxyquinoline-3-carboxylate was as follows: ethyl 4-hydroxyquinoline-3-carboxylate (1.2 g, 5.5 mmol) was dissolved in 20 mL of ethanol, followed by the addition of 0.1 g/mL of aqueous sodium hydroxide (6.6 mL, 16.5 mmol). The reaction was carried out under reflux conditions for 3 hours. Upon completion of the reaction, the reaction solution was cooled to 20 °C and the pH was adjusted to 4 with 4 mol/L hydrochloric acid, at which point a solid precipitated. After recovering about 10 mL of solvent ethanol by decompression distillation, the solid was collected by filtration. The solid was washed with a mixture of ethanol and water (2 mL x 2 times) and finally dried to give 0.96 g of 4-hydroxyquinoline-3-carboxylic acid in 92% yield and the product was an off-white solid.
References
[1] Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2000, vol. 344, p. 163 - 168
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 2, p. 167 - 175
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 2, p. 195 - 203
[4] Patent: CN106187887, 2016, A. Location in patent: Paragraph 0015; 0048; 0049; 0050; 0051; 0052; 0053
[5] Journal of the American Chemical Society, 1946, vol. 68, p. 1264
4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9694 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49860 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 | nickzhang@hangyubiotech.com | China | 9930 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
View Lastest Price from 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
34785-11-0
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-07-06 | 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
34785-11-0
|
$2.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
34785-11-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
34785-11-0
- $2.00
- 99%
- Career Henan Chemical Co
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