6-Amino-2-methyl-2H-indazole
- CAS No.
- 50593-30-1
- Chemical Name:
- 6-Amino-2-methyl-2H-indazole
- Synonyms
- 2-Methyl-2H-indazol-6-amine;2-Methyl-2H-indazole-6-amine;6-aMine-2-Methyl-2H-indazole;6-Amino-2-methyl-2H-indaz...;6-Amino-2-methyl-2H-indazole;2H-Indazol-6-amine, 2-methyl-;6-AMINO-2-METHYLBENZO[C]PYRAZOLE
- CBNumber:
- CB5733477
- Molecular Formula:
- C8H9N3
- Molecular Weight:
- 147.18
- MDL Number:
- MFCD00464866
- MOL File:
- 50593-30-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 148-150 |
|---|---|
| Boiling point | 354.8±15.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 3.31±0.10(Predicted) |
| form | Crystalline Powder |
| color | Yellow to green |
| InChI | InChI=1S/C8H9N3/c1-11-5-6-2-3-7(9)4-8(6)10-11/h2-5H,9H2,1H3 |
| InChIKey | MHCWLERQNFATHZ-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=CC(N)=C2)=CN1C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 29339980 |
6-Amino-2-methyl-2H-indazole price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR3688 | 6-Amino-2-methyl-2H-indazole ≥95% | 50593-30-1 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR3688 | 6-Amino-2-methyl-2H-indazole ≥95% | 50593-30-1 | 1g | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR3688 | 6-Amino-2-methyl-2H-indazole ≥95% | 50593-30-1 | 5g | $123 | 2026-06-04 | Buy |
| Apolloscientific | OR3688 | 6-Amino-2-methyl-2H-indazole ≥95% | 50593-30-1 | 25g | $613 | 2026-06-04 | Buy |
| Activate Scientific | AS1041 | 6-Amino-2-methylindazole 97% | 50593-30-1 | 1g | $62 | 2026-06-04 | Buy |
6-Amino-2-methyl-2H-indazole Chemical Properties, Uses, Production
Appearance
Brown crystalline powder
Uses
2-Methyl-2H-indazol-6-ylamine is a research chemical that can be used as a pharmaceutical intermediate.
Synthesis
6850-22-2
50593-30-1
General procedure for the synthesis of 2-methyl-6-amino-2H-indazole from 2-methyl-6-nitro-2H-indazole: 10% palladium-carbon catalyst (51.7% in water, 1 g) was added to a solution of 2-methyl-6-nitro-2H-indazole (7.50 g, 40 mmol) in ethanol (150 ml). The reaction mixture was placed under hydrogen atmosphere and stirred at room temperature for 12 hours. After completion of the reaction, the catalyst was removed by filtration and the catalyst residue was washed with ethanol. The filtrate and washings were combined and the solvent was removed by distillation under reduced pressure to afford the target product 2-methyl-6-amino-2H-indazole as a light beige solid (6.05 g, 95.0% yield).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 4, p. 1108 - 1110
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988, p. 403 - 409
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1988, vol. 24, # 4, p. 491 - 498
[4] Journal of Chemical Research, Miniprint, 1990, # 11, p. 2601 - 2615
[5] Heterocycles, 1995, vol. 41, # 3, p. 487 - 496
6-Amino-2-methyl-2H-indazole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
6-Amino-2-methyl-2H-indazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1401 | 59 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3995 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| EnliPharma Technology Co., Ltd | 0551-66399836 18955197623 | sales@enlipharma.com | China | 1875 | 55 |
