SULFURETIN
- CAS No.
- 120-05-8
- Chemical Name:
- SULFURETIN
- Synonyms
- (Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one;SULFURETIN;SULPHURETIN;SULFURETIN hplc;SULFURETIN WITH HPLC;3',4',6-TRIHYDROXYAURONE;6,3',4'-TRIHYDROXYAURONE;3',4',6-Trihydroxybenzalcoumaranone;2-(3,4-dihydroxybenzylidene)-6-hydroxy-2H-benzofuran-3-one;2-(3,4-Dihydroxybenzylidene)-6-hydroxy-3(2H)-benzofuranone
- CBNumber:
- CB5774890
- Molecular Formula:
- C15H10O5
- Molecular Weight:
- 270.24
- MDL Number:
- MFCD00017304
- MOL File:
- 120-05-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Sulfuretin ≥98% (HPLC) | SML3002 | 5MG | $170 |
| Sulfuretin ≥98% | 36569 | 1mg | $32 |
| Sulfuretin ≥98% | 36569 | 5mg | $127 |
| Sulfuretin ≥98% | 36569 | 10mg | $237 |
| Sulfuretin ≥98% | 36569 | 25mg | $550 |
| Melting point | 295°C |
|---|---|
| storage temp. | 2-8°C |
| solubility |
Acetone: Soluble Chloroform: Soluble Dichloromethane: Soluble DMSO: SolubleEthyl Acetate: Soluble |
| form | Solid |
| color | Yellow to orange |
| InChI | 1S/C15H10O5/c16-9-2-3-10-13(7-9)20-14(15(10)19)6-8-1-4-11(17)12(18)5-8/h1-7,16-18H/b14-6- |
| InChIKey | RGNXWPVNPFAADO-NSIKDUERSA-N |
| SMILES | OC1=CC=C2C(O/C(C2=O)=C\C3=CC(O)=C(O)C=C3)=C1 |
| LogP | 1.980 (est) |
| FDA UNII | M6410VY6MI |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SULFURETIN price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3002 | Sulfuretin ≥98% (HPLC) | 120-05-8 | 5MG | $170 | 2026-04-30 | Buy |
| Cayman Chemical | 36569 | Sulfuretin ≥98% | 120-05-8 | 1mg | $32 | 2026-04-30 | Buy |
| Cayman Chemical | 36569 | Sulfuretin ≥98% | 120-05-8 | 5mg | $127 | 2026-04-30 | Buy |
| Cayman Chemical | 36569 | Sulfuretin ≥98% | 120-05-8 | 10mg | $237 | 2026-04-30 | Buy |
| Cayman Chemical | 36569 | Sulfuretin ≥98% | 120-05-8 | 25mg | $550 | 2026-04-30 | Buy |
SULFURETIN Chemical Properties,Uses,Production
Uses
Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].
Definition
ChEBI: Sulfuretin is a member of 1-benzofurans.
Biological Activity
Anti-adipogenic, antineoplastic activity, antioxidative stress, Anti-Inflammatory
in vivo
Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation[1].
| Animal Model: | Pathogen-free male BALB/c mice (7-8 weeks old)[1] |
| Dosage: | 40 μg/kg |
| Administration: | A single intraperitoneal injection was administered 2 h after the last OVA challenge |
| Result: | Suppressed OVA-induced chemotaxis and airway inflammation. |
References
[1] Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400(1):83-8. DOI:10.1016/j.bbrc.2010.08.014
[2] Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11(1), 759-771.
[3] SO YOUNG KANG Myung J O Ji Young Kang. Antiviral activities of flavonoids isolated from the bark of Rhus verniciflua stokes against fish pathogenic viruses In Vitro.[J]. Journal of Microbiology, 2012, 50 2: 293-300. DOI: 10.1007/s12275-012-2068-7
SULFURETIN Preparation Products And Raw materials
Raw materials
Preparation Products
SULFURETIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +86-18080483897 | sales@biopurify.com | China | 4616 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Winherb Medical Technology Co., Ltd. | 17301719108 13341702378 | winherb@126.com | China | 1245 | 58 |
