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ChemicalBook >> CAS DataBase List >>Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)-

Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)-

Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- Structure
Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- structure
CAS No.
297744-42-4
Chemical Name:
Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)-
Synonyms
T28012;MEK-IN-4;Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)-
CBNumber:
CB58203226
Molecular Formula:
C21H18N4OS
Molecular Weight:
374.46
MDL Number:
MOL File:
297744-42-4.mol
Last updated:2025-10-10 22:54:41
Product description Number Pack Size Price
MEK Inhibitor I - CAS 297744-42-4 - Calbiochemv 444937 1MG $177
MEK Inhibitor I - CAS 297744-42-4 - Calbiochemv 444937 5MG $586
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Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- Properties

Boiling point 671.9±55.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: 10mg/mL
methanol: 50mg/mL
pka 12.38±0.20(Predicted)
form solid
color white
UNSPSC Code 12352200
NACRES NA.77

Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 444937 MEK Inhibitor I - CAS 297744-42-4 - Calbiochemv 297744-42-4 1MG $177 2025-07-31 Buy
Sigma-Aldrich 444937 MEK Inhibitor I - CAS 297744-42-4 - Calbiochemv 297744-42-4 5MG $586 2023-06-20 Buy
Product number Packaging Price Buy
444937 1MG $177 Buy
444937 5MG $586 Buy

Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- Chemical Properties,Uses,Production

Uses

MEK-IN-4 is a MEK inhibitor. MEK-IN-4 can be used for the research of inflammatory disorders and cancers[1].

Biological Activity

Cell permeable: yes', 'Primary Target
MEK', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 12 nM against MEK

References

[1] Frank W. Hobbs, et al. Amino-thio-acrylonitriles as mek inhibitors. Patent. WO2000056706A1.

Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1248 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24989 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 024-024-024-88590548 18341751992 757984502@qq.com China 941 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 086-15871494362 13720134139 orders@jknbiochem.com China 6264 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5881 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Shandong Mopai Biotechnology Co., Ltd 13053322091 admin@mopaikeji.com China 5813 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 400-6206333 13167063860 anhua.mao@aladdin-e.com China 48457 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shandong Mopai Biotechnology Co., Ltd 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58

View Lastest Price from Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MEK-IN-4 pictures 2025-10-10 MEK-IN-4
297744-42-4
 US $912.00-210.00 / mg 99.16% 10g TargetMol Chemicals Inc.
  • MEK-IN-4 pictures
  • MEK-IN-4
    297744-42-4
  • US $912.00-210.00 / mg
  • 99.16%
  • TargetMol Chemicals Inc.
Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)- MEK-IN-4 T28012 297744-42-4