Ethyl 5-formyl-1H-pyrrole-2-carboxylate
- CAS No.
- 7126-50-3
- Chemical Name:
- Ethyl 5-formyl-1H-pyrrole-2-carboxylate
- Synonyms
- Ethyl 5-formyl-1H-pyrrole-2-carboxylate;1H-Pyrrole-2-carboxylic acid, 5-forMyl-, ethyl ester
- CBNumber:
- CB5832020
- Molecular Formula:
- C8H9NO3
- Molecular Weight:
- 167.16
- MDL Number:
- MFCD00159462
- MOL File:
- 7126-50-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933998090 |
Ethyl 5-formyl-1H-pyrrole-2-carboxylate price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 61434 | ETHYL 5-FORMYLPYRROLE-2-CARBOXYLATE 97% | 7126-50-3 | 1G | $78 | 2026-04-30 | Buy |
| AstaTech | 61434 | ETHYL 5-FORMYLPYRROLE-2-CARBOXYLATE 97% | 7126-50-3 | 5G | $290 | 2026-04-30 | Buy |
| Apolloscientific | OR912411 | Ethyl 5-formyl-1H-pyrrole-2-carboxylate >97% | 7126-50-3 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR912411 | Ethyl 5-formyl-1H-pyrrole-2-carboxylate >97% | 7126-50-3 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR912411 | Ethyl 5-formyl-1H-pyrrole-2-carboxylate >97% | 7126-50-3 | 1g | $29 | 2026-06-04 | Buy |
Ethyl 5-formyl-1H-pyrrole-2-carboxylate Chemical Properties,Uses,Production
Synthesis
2199-43-1
68-12-2
7126-50-3
7126-57-0
A-6 Synthesis of ethyl 5-formyl-1H-pyrrole-2-carboxylate and ethyl 4-formyl-1H-pyrrole-2-carboxylate Procedure: 75 mL of dichloromethane solution of phosphorus trichloride (25 mL, 0.27 mol) was slowly added to 75 mL of dichloroethane solution of N,N-dimethylformamide (21 mL, 0.27 mol) at 0 °C. The reaction mixture was stirred at room temperature for 30 minutes and then cooled to 0°C again. Subsequently, a solution of ethyl pyrrole-2-carboxylate (25 g, 0.18 mol) dissolved in 50 mL of dichloroethane was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was stirred at room temperature for 30 minutes and then continued stirring at 40 °C for 1 hour. After completion of the reaction, the mixture was carefully poured into ice water and the pH was adjusted to 11 with 5N sodium hydroxide solution.The reaction mixture was extracted with ethyl acetate, the organic phases were combined, washed sequentially with water and saturated saline, and finally dried with anhydrous sodium sulfate. Separation by column chromatography (eluent ratio 1:3 ethyl acetate:hexane) gave 15 g (50% yield) of ethyl 5-formyl-1H-pyrrole-2-carboxylate and 2 g (7% yield) of ethyl 4-formyl-1H-pyrrole-2-carboxylate. The products were confirmed by 1H-NMR (300 MHz, dimethylsulfoxide-d6) and mass spectrometry: 1H-NMR δ 13.02 (br s, 1H, NH), 9.69 (s, 1H, CHO), 6.95 (d, 1H), 6.86 (d, 1H), 4.27 (q, 2H, CH2), 1.28 (t, 3H, CH3). ms m/z 167 [M+].
References
[1] Journal of Organic Chemistry, 1993, vol. 58, # 25, p. 7245 - 7257
[2] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 14, p. 6911 - 6923
[3] Patent: US2004/204407, 2004, A1. Location in patent: Page/Page column 16
[4] Patent: US2004/204407, 2004, A1. Location in patent: Page/Page column 21
[5] Patent: US2004/266843, 2004, A1. Location in patent: Page 12
Ethyl 5-formyl-1H-pyrrole-2-carboxylate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shangchem Co., Ltd. | +86-21-68182121 | China | 881 | 52 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| HANSHANG CHEMICAL SCIENTIFIC LIMITED | 021-50521775 15800962688 | sales@hanshangchem.com | China | 471 | 57 |
| skychemical Co.Ltd | 021-20958197 20965099 | sales@skychemical.com | China | 1182 | 57 |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| ZhengZhou HuaWen Chemical Co.Ltd | 0370-2785118 17550508557 | 675141927@qq.com | China | 3201 | 55 |
View Lastest Price from Ethyl 5-formyl-1H-pyrrole-2-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | ETHYL 5-FORMYL-1H-PYRROLE-2-CARBOXYLATE
7126-50-3
|
$6.00 | 1KG | 98% | 1kg, 5kg, 50kg | Career Henan Chemical Co |
-
- ETHYL 5-FORMYL-1H-PYRROLE-2-CARBOXYLATE
7126-50-3
- $6.00
- 98%
- Career Henan Chemical Co
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