ChemicalBook >> CAS DataBase List >>L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl-

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl-

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl- structure

CAS No.: 2426685-25-6

Chemical Name:: L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl-

Synonyms: L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl-

CBNumber:: CB58378302

Molecular Formula:: C107H150N34O32S2

Molecular Weight:: 2488.7

MDL Number:

MOL File:: 2426685-25-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:24

Request For Quotation

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl- Properties

Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
form	Solid
color	White to off-white

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0148180	TPP-1 99.13%	2426685-25-6	5mg	$195	2026-06-04	Buy
ChemScene	CS-0148180	TPP-1 99.13%	2426685-25-6	10mg	$325	2026-06-04	Buy
ChemScene	CS-0148180	TPP-1 99.13%	2426685-25-6	25mg	$650	2026-06-04	Buy
ApexBio Technology	BA6149	TPP-1	2426685-25-6	1mg	$54	2026-05-06	Buy
ApexBio Technology	BA6149	TPP-1	2426685-25-6	5mg	$162	2026-05-06	Buy

Product number	Packaging	Price	Buy
CS-0148180	5mg	$195	Buy
CS-0148180	10mg	$325	Buy
CS-0148180	25mg	$650	Buy
BA6149	1mg	$54	Buy
BA6149	5mg	$162	Buy

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl- Chemical Properties, Uses, Production

Uses

TPP-1 is a potent inhibitor of thePD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function[1].

in vivo

TPP-1 (subcutaneous injection; 4 mg/kg; every other day eight times; 32 days) inhibits tumor growth (compared with SPP-1 and control). The growth rate in TPP-1-treated mice is 56%. And when administered in the absence of T cells (control group), TPP-1 has no effect on the growth of the H460-luc tumors^[1].

Animal Model:	5 to 6-week-old female Balb/c nude mice injected with H460 cells transfected with the plvx-puro/luciferase lentiviral vector^[1]
Dosage:	4 mg/kg
Administration:	Subcutaneous injection; 4 mg/kg; every other day eight times; 32days
Result:	Inhibited the tumor growth in a tumor xenograft model via reactivating T-cell function.

References

[1] Chunlin Li, et al. Peptide Blocking of PD-1/PD-L1 Interaction for Cancer Immunotherapy. Cancer Immunol Res. 2018 Feb;6(2):178-188. DOI:10.1158/2326-6066.CIR-17-0035

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl- Preparation Products And Raw materials

Raw materials

Preparation Products

L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl- Suppliers

Global Suppliers ( 14)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9729	58
Chengdu Youngshe Chemical Co., Ltd.	+86-17380623303	Caroline@youngshechem.com	China	4726	58
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10378	58
Wuxi Helen Biotechnology Co., Ltd.,	0510-85629785 18013409632	sales@reading-chemicals.com	China	14072	58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD	0571-87213919 17306812703	3007955328@qq.com	China	7446	58
Shanghai HongTide Biotechnology Co.,Ltd.	15318089928	alex@hanhonggroup.com	China	4604	58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd	18020125070	sales002@jszkhy.com	China	2105	58
YantaiBio	13758194781; 13758194781	764619768@qq.com	China	1755	58
Fuan Bio	15002819872	2845971812@qq.com	China	2103	58

Supplier	Advantage
Shanghai Chaolan Chemical Technology Center	58
Chengdu Youngshe Chemical Co., Ltd.	58
Hangzhou Peptidego Biotech Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Wuxi Helen Biotechnology Co., Ltd.,	58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD	58
Shanghai HongTide Biotechnology Co.,Ltd.	58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd	58
YantaiBio	58
Fuan Bio	58

2426685-25-6 (L-Lysine, L-serylglycyl-L-glutaminyl-L-tyrosyl-L-alanyl-L-seryl-L-tyrosyl-L-histidyl-L-cysteinyl-L-tryptophyl-L-cysteinyl-L-tryptophyl-L-arginyl-L-α-aspartyl-L-prolylglycyl-L-arginyl-L-serylglycylglycyl-L-seryl-) Related Search:

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