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2-methoxypropionic acid

CAS No.
4324-37-2
Chemical Name:
2-methoxypropionic acid
Synonyms
2-methoxypropanoic acid;Propanoic acid, 2-methoxy-;2021.11.2;UNII:288B9CW12D;Einecs 224-356-3;2-Methoxypropionsure;2-methoxypropionic acid;alpha-Methoxypropionic acid;2-methoxypropanoic acid(SALTDATA: FREE)
CBNumber:
CB5915226
Molecular Formula:
C4H8O3
Molecular Weight:
104.1
MDL Number:
MFCD00126928
MOL File:
4324-37-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:30:25
Product description Number Pack Size Price
2-Methoxypropanoic acid TRC-M267198-100MG 100mg $73
2-Methoxypropanoic acid 048808 25.00g $43
2-Methoxypropanoic acid 048808 100.00g $131
2-Methoxypropanoic acid 048808 500.00g $655
2-Methoxypropionic Acid 97% M69861 1g $10
More product size

2-methoxypropionic acid Properties

Melting point 128.5 °C
Boiling point 199℃
Density 1.085
Flash point 87℃
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
pka 3.59±0.10(Predicted)
color Colorless
InChI InChI=1S/C4H8O3/c1-3(7-2)4(5)6/h3H,1-2H3,(H,5,6)
InChIKey ICPWFHKNYYRBSZ-UHFFFAOYSA-N
SMILES C(O)(=O)C(OC)C
FDA UNII 288B9CW12D

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
HazardClass  IRRITANT

2-methoxypropionic acid price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-M267198-100MG 2-Methoxypropanoic acid 4324-37-2 100mg $73 2026-06-03 Buy
Matrix Scientific 048808 2-Methoxypropanoic acid 4324-37-2 25.00g $43 2026-05-18 Buy
Matrix Scientific 048808 2-Methoxypropanoic acid 4324-37-2 100.00g $131 2026-05-18 Buy
Matrix Scientific 048808 2-Methoxypropanoic acid 4324-37-2 500.00g $655 2026-05-18 Buy
Synthonix M69861 2-Methoxypropionic Acid 97% 4324-37-2 1g $10 2026-05-06 Buy
Product number Packaging Price Buy
TRC-M267198-100MG 100mg $73 Buy
048808 25.00g $43 Buy
048808 100.00g $131 Buy
048808 500.00g $655 Buy
M69861 1g $10 Buy

2-methoxypropionic acid Chemical Properties,Uses,Production

Synthesis

Sodium Methoxide

124-41-4

2-Bromopropionic acid

598-72-1

2-methoxypropionic acid

4324-37-2

A methanolic solution of 25% sodium methanolate (16 mL) was slowly added dropwise to a stirring solution of 2-bromopropionic acid (19.6 mmol) in methanol (5 mL) under nitrogen protection. The reaction mixture was heated and reacted at 50 °C overnight while continuously protected by the passage of nitrogen. Upon completion of the reaction, the reaction solution was concentrated under reduced pressure by rotary evaporator. The residue was adjusted to pH 1 with aqueous 1N hydrochloric acid, followed by three extractions with ethyl acetate (70 mL, 25 mL, 10 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated again under reduced pressure to afford 2-methoxypropionic acid as a colorless oil in the yield of 2.04 g (99% yield), which was pure enough to be used directly in the subsequent reaction without further purification. The product was characterized by 1H NMR (CD3OD): δ 3.67 (q, 1H), 3.33 (s, 3H), 1.33 ppm (d, 3H).

References

[1] Patent: WO2006/96338, 2006, A1. Location in patent: Page/Page column 41
[2] Patent: WO2006/133006, 2006, A2. Location in patent: Page/Page column 46-47
[3] Australian Journal of Chemistry, 1980, vol. 33, # 4, p. 809 - 821
[4] Organic Letters, 2018, vol. 20, # 16, p. 4867 - 4870
[5] Patent: KR2015/128789, 2015, A. Location in patent: Paragraph 0896; 0898; 0899

124-41-4
598-72-1
4324-37-2
Synthesis of 2-methoxypropionic acid from Sodium Methoxide and 2-Bromopropionic acid
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View Lastest Price from 2-methoxypropionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-methoxypropionic acid pictures 2019-12-26 2-methoxypropionic acid
4324-37-2
$1.00 1KG 99% 1000KGS Career Henan Chemical Co

2-methoxypropionic acid Spectrum

Einecs 224-356-3 2-methoxypropanoic acid(SALTDATA: FREE) 2-methoxypropionic acid alpha-Methoxypropionic acid 2-Methoxypropionsure 2021.11.2 UNII:288B9CW12D 2-methoxypropanoic acid Propanoic acid, 2-methoxy- 4324-37-2