3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate
- CAS No.
- 59256-52-9
- Chemical Name:
- 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate
- Synonyms
- Einecs 261-677-8;Bis-acrylate-PEG5;3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate;Bispropenoic acid 3,6,9,12-tetraoxatetradecane-1,14-diyl ester;14-(prop-2-enoyloxy)-3,6,9,12-tetraoxatetradecan-1-yl prop-2-enoate;2-Propenoic acid,3,6,9,12-tetraoxatetradecane-1,14-diyl ester (9CI);2-Propenoic acid, 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl) ester
- CBNumber:
- CB5930722
- Molecular Formula:
- C16H26O8
- Molecular Weight:
- 346.37
- MDL Number:
- MFCD32706469
- MOL File:
- 59256-52-9.mol
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Chemical Properties,Uses,Production
Uses
Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Preparation Products And Raw materials
Raw materials
Preparation Products
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Aikon International Limited | 025-66113011 13155353615 | qzhang@aikonchem.com | China | 15393 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13482353728 | sales@fdc-chemical.com | China | 9807 | 58 |
| Amel Pharmatech Corporation | 027-888-4366503 | sales@amelpharmatech.com | China | 4997 | 58 |
| Shaanxi borno biotechnology co., LTD | +86-13759708231 | asherw9@hotmail.com | China | 2373 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49312 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| Henan Kehong Biological Technology Co. LTD | 0371-86658258 ；0371-55969461 | info@kehobio.com | China | 2748 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59936 | 58 |
