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| | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Basic information |
| Product Name: | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate | | Synonyms: | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate;Bispropenoic acid 3,6,9,12-tetraoxatetradecane-1,14-diyl ester;Einecs 261-677-8;2-Propenoic acid, 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl) ester;Bis-acrylate-PEG5;2-Propenoic acid,3,6,9,12-tetraoxatetradecane-1,14-diyl ester (9CI);14-(prop-2-enoyloxy)-3,6,9,12-tetraoxatetradecan-1-yl prop-2-enoate | | CAS: | 59256-52-9 | | MF: | C16H26O8 | | MW: | 346.37 | | EINECS: | 2616778 | | Product Categories: | | | Mol File: | 59256-52-9.mol |  |
| | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Chemical Properties |
| | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Usage And Synthesis |
| Uses | Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Preparation Products And Raw materials |
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