canadine
- CAS No.
- 5096-57-1
- Chemical Name:
- canadine
- Synonyms
- (S)-Canadine;C03329;(-)-Canadine;Canadine l-form;(S)-Tetrahydroberberine;(13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-
- CBNumber:
- CB5939134
- Molecular Formula:
- C20H21NO4
- Molecular Weight:
- 339.39
- MDL Number:
- MFCD00236139
- MOL File:
- 5096-57-1.mol
- MSDS File:
- SDS
| Melting point | 135° |
|---|---|
| alpha | D22 -308°; -317° (c = 0.28; 0.4, both in methanol) |
| Boiling point | 475.36°C (rough estimate) |
| Density | 1.2270 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Refrigerator |
| solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated) |
| form | Solid |
| pka | 6.53±0.20(Predicted) |
| color | Pale Yellow to Light Yellow |
| FDA UNII | Q97V5BUT9D |
canadine price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 33805 | (S)-Canadine ≥98% | 5096-57-1 | 1mg | $29 | 2026-04-30 | Buy |
| Cayman Chemical | 33805 | (S)-Canadine ≥98% | 5096-57-1 | 5mg | $120 | 2026-04-30 | Buy |
| Cayman Chemical | 33805 | (S)-Canadine ≥98% | 5096-57-1 | 10mg | $212 | 2026-04-30 | Buy |
| TRC | TRC-C175180-25MG | (S)-(-)-Canadine | 5096-57-1 | 25mg | $272 | 2026-06-03 | Buy |
| TRC | TRC-C175180-250MG | (S)-(-)-Canadine | 5096-57-1 | 250mg | $1967 | 2026-06-03 | Buy |
canadine Chemical Properties, Uses, Production
Chemical Properties
Yellow Solid
Uses
(S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
Definition
ChEBI: (S)-canadine is the (S)-enantiomer of canadine. It has a role as a plant metabolite. It is functionally related to a (S)-nandinine. It is an enantiomer of a (R)-canadine.
target
P450 (e.g. CYP17)
canadine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2992 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
