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ChemicalBook >> CAS DataBase List >>(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Structure
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol structure
CAS No.
209414-27-7
Chemical Name:
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
Synonyms
(2S)-2-(2-aMino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol;Efavirenz IP Imp E;Efavirenz USP RC A;Efavirenz Impurity 5;Efavirenz IP Impurity E;Efavirenz Related CoMpound A;Efavirenz USP Related Compound A;(S)-2-(2-Amino-5-chlorophenyl)-4-cy;Efavirenz Impurity 5(Efavirenz IP Impurity E);(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopr...
CBNumber:
CB5948781
Molecular Formula:
C13H11ClF3NO
Molecular Weight:
289.68
MDL Number:
MFCD09751012
MOL File:
209414-27-7.mol
MSDS File:
SDS
Last updated:2026-05-28 03:26:44
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(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Properties

Melting point 134-136°C
Boiling point 425.1±45.0 °C(Predicted)
Density 1.46
storage temp. 2-8°C(protect from light)
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 9.13±0.24(Predicted)
color White to Off-White
Major Application pharmaceutical
InChI 1S/C13H11ClF3NO/c14-9-3-4-11(18)10(7-9)12(19,13(15,16)17)6-5-8-1-2-8/h3-4,7-8,19H,1-2,18H2/t12-/m0/s1
InChIKey KEMUGFRERPPUHB-LBPRGKRZSA-N
SMILES FC(F)(F)[C@@](O)(c2c(ccc(c2)Cl)N)C#CC1CC1
FDA UNII Z3E01963ZY
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  WGK 3
HS Code  2922199695
Storage Class 11 - Combustible Solids

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2068 Efavirenz Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 209414-27-7 50mg $566 2026-04-30 Buy
Sigma-Aldrich 1234125 Efavirenz Related Compound A 209414-27-7 20mg $1140 2026-04-30 Buy
aablocks AA002K5T (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95% 209414-27-7 1g $39 2026-05-28 Buy
aablocks AA002K5T (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95% 209414-27-7 5g $131 2026-05-28 Buy
Crysdot CD12096937 (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95+% 209414-27-7 1g $465 2026-05-27 Buy
Product number Packaging Price Buy
PHR2068 50mg $566 Buy
1234125 20mg $1140 Buy
AA002K5T 1g $39 Buy
AA002K5T 5g $131 Buy
CD12096937 1g $465 Buy

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Chemical Properties, Uses, Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of Efavirenz (E425000) impurity.

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol synthesis

6746-94-7
154598-53-5
209414-27-7
Synthesis of (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol from Cyclopropylacetylene and 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Preparation Products And Raw materials

Raw materials

Propanamide, N-(2-bromo-4-chlorophenyl)-2,2-dimethyl- Magnesium, chloro(2-cyclopropylethynyl)- 1352784-90-7 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone 4-Chloro-(N-Boc)aniline 97
Cyclopropylacetylene 2,2,2-Trifluoroethanol

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Preparation Products

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Suppliers

Global Suppliers ( 124)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16306 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7917 65
Syntechem Co.,Ltd info@syntechem.com China 12973 57
China Langchem Inc. 0086-21-58956006 China 7798 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
SynAsst Chemical. 021-60343070 China 12731 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Nanjing Chemlin Chemical Co., Ltd 64
Chemsky（shanghai）International Co.,Ltd. 50
Daicel Chiral Technologies (China)CO.,LTD 65
Syntechem Co.,Ltd 57
China Langchem Inc. 57
Sinopharm Chemical Reagent Co,Ltd. 79
BioBioPha Co., Ltd. 65
Shanghai T&W Pharmaceutical Co., Ltd. 58
SynAsst Chemical. 55

View Latest Price from (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol pictures 2026-09-02 (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
209414-27-7
 $5.00 1KG 98% Henan Fengda Chemical Co., Ltd
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol pictures 2019-07-06 (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
209414-27-7
 $7.00 1kg 99% 100kg Career Henan Chemical Co
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol pictures 2019-07-06 (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
209414-27-7
 $7.00 1kg 99% 100kg Career Henan Chemical Co

209414-27-7 ((S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol) Related Search:

3-Methyl-2-butanone 6-Aminocaproic acid Cyclopropyl methyl ketone Lithium diisopropylamide 3-Aminophenol
3-Chloropropyne Chlorodimethylphenylsilane Propargyl bromide Tris(hydroxymethyl)aminomethane Glycine
Aminoethoxyvinyl glycine hydrochloride (S)-5-chloro-a-(Cyclopropylacetenyl)-2-[((4-methoxyphenyl)methyl)amino]-a- (trifluoromethyl) benzenemethanol (E-4) Efavirenz Efavirenz IP Impurity A Efavirenz Related Compound B (15 mg) ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one)
rac 8-Hydroxy Efavirenz rac 8,14-Dihydroxy Efavirenz rac 7-Hydroxy Efavirenz

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BenzeneMethanol,2-aMino-5-chloro-a-(2-cyclopropylethynyl)-a-(trifluoroMethyl)-, (aS)- (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol Efavirenz Impurity 5(Efavirenz IP Impurity E) (2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol Efavirenz IP Imp E (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (E05) (2R)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol (R)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol (S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol (S)-1-(2-AMINO-5-CHLOROPHENYL)-1-(TRIFLUOROMETHYL)-3-CYCLOPROPYL-2-PROPYN-1-OL (S)-5-CHLORO-A-(CYCLOPROPYLETHYNYL)-2-AMINO-A-(TRIFLUOROMETHYL)BENZENE METHANOL Efavirenz Related Compound A (20 mg) ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol) Efavirenz Related CoMpound A (S)-1-(2-AMino-5-chlorophenyl)-1-(trifluoroMethyl)-3-cyclopropyl-2-propyn-1-ol (E6) 1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (S)-5-Chloro-Alpha-(Cyclopropylethynyl-2-Amino-Alpha-(Triflumethanolmethyl)-Benzenemethanol Efavirenz USP Related Compound A (S)-2-(2-Amino-5-chlorophenyl)-4-cy Efavirenz IP Impurity E Benzenemethanol, 2-amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)-, (αS)- Efavirenz Impurity 5 (S)-1-(2-AMINO-5-CHLOROPHENYL)-1-(TRIFLUOROMETHYL)-3-CYCLOPROPYL-2-PROPYN-1-OL (E05) CAS 209414-27-7 Efavirenz USP RC A Efavirenz Related Compound A/ Efavirenz IP Impurity E (Efavirenz Amino Alcohol/ Efavirenz amino carbinol) (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopr... Efavirenz Related Compound A ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn- (1234125) (αS)-2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 98% (alphaS)-2-Amino-5-chloro-alpha-(2-cyclopropylethynyl)-alpha-(trifluoromethyl)-benzenemethanol Efavirenz Impurity: (S)-2-(2-Amino-5-Chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol (2S)-2-(2-aMino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 209414-27-7