ChemicalBook >> CAS DataBase List >>3-[(2-Pyridinyl)methylene]indolin-2-one
3-[(2-Pyridinyl)methylene]indolin-2-one
![3-[(2-Pyridinyl)methylene]indolin-2-one Structure](CAS/20211123/GIF/3367-88-2.gif)
- CAS No.
- 3367-88-2
- Chemical Name:
- 3-[(2-Pyridinyl)methylene]indolin-2-one
- Synonyms
- (E/Z)- SK-3inhibitor 1;(E/Z)-GSK-3inhibitor 1;(E/Z)-GSK-3β inhibitor 1;(E/Z)-GSK-3β inhibitor 1 ，E0381;3-(Pyridin-2-ylmethylene)indolin-2-one;3-[(2-Pyridinyl)methylene]indolin-2-one;(E/Z)-GSK-3β inhibitor 1, 10 mM in DMSO;3-(pyridin-2-ylmethylidene)-1H-indol-2-one;Glycogen synthase kinase 3,Inhibitor,Glycogen synthase kinase-3,inhibit,(E/Z)GSK3β inhibitor 1,GSK-3,(E/Z) GSK 3β inhibitor 1
- CBNumber:
- CB59664651
- Molecular Formula:
- C14H10N2O
- Molecular Weight:
- 222.25
- MDL Number:
- MFCD00022808
- MOL File:
- 3367-88-2.mol
- MSDS File:
- SDS
Last updated:2026-07-27 17:00:41
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
3-[(2-Pyridinyl)methylene]indolin-2-one price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0134168 | (E/Z)-GSK-3β inhibitor 1 99.10% | 3367-88-2 | 5mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-0134168 | (E/Z)-GSK-3β inhibitor 1 99.10% | 3367-88-2 | 10mg | $282 | 2026-06-04 | Buy |
| ChemScene | CS-0134168 | (E/Z)-GSK-3β inhibitor 1 99.10% | 3367-88-2 | 50mg | $845 | 2026-06-04 | Buy |
| aablocks | AA01GA2E | 3-(pyridin-2-ylmethylidene)-1,3-dihydro-2H-indol-2-one | 3367-88-2 | 2mg | $46 | 2026-05-30 | Buy |
| aablocks | AA01GA2E | 3-(pyridin-2-ylmethylidene)-1,3-dihydro-2H-indol-2-one | 3367-88-2 | 5mg | $64 | 2026-05-30 | Buy |
3-[(2-Pyridinyl)methylene]indolin-2-one Chemical Properties, Uses, Production
Uses
(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].
References
[1] Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817. DOI:10.1016/j.bmc.2019.03.028
3-[(2-Pyridinyl)methylene]indolin-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
3-[(2-Pyridinyl)methylene]indolin-2-one Suppliers
Global Suppliers ( 29)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 18916372613 | yanzihan@shyuanye.com | China | 87240 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9773 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Wuxi Donghe Pharmaceutical Technology Co., Ltd. | 63313187 15358055255 | 63313187@qq.com | China | 1981 | 58 |
| Shandong Jirun Biomedical Technology Co., Ltd. | 0539-0539-8613587 17661611089 | 2639273505@qq.com | China | 240 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
View Latest Price from 3-[(2-Pyridinyl)methylene]indolin-2-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | (E/Z)-GSK-3β inhibitor 1
3367-88-2
|
$32.00-98.00 | 99.80% | 10g | TargetMol Chemicals Inc. |
-
- (E/Z)-GSK-3β inhibitor 1
3367-88-2
- $32.00-98.00
- 99.80%
- TargetMol Chemicals Inc.
3367-88-2 (3-[(2-Pyridinyl)methylene]indolin-2-one) Related Search:
(Z)-3-((2-Aminophenyl)(1H-indol-2-yl)methylene)-1-(naphthalen-2-ylmethyl)indolin-2-one
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3-phenyl-1,5-naphthyridin-2-ol
2H-Indol-2-one, 1,3-dihydro-3-(2-pyridinylmethylene)-, (3Z)-
1H-Pyrrole-3-carboxamide, 5-[(Z)-[5-[(aminocarbonyl)amino]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-N-[2-(dimethylamino)ethyl]-
1of2
3-[(2-Pyridinyl)methylene]indolin-2-one
(E/Z)-GSK-3inhibitor 1
(E/Z)-GSK-3β inhibitor 1
3-(Pyridin-2-ylmethylene)indolin-2-one
Glycogen synthase kinase 3,Inhibitor,Glycogen synthase kinase-3,inhibit,(E/Z)GSK3β inhibitor 1,GSK-3,(E/Z) GSK 3β inhibitor 1
(E/Z)- SK-3inhibitor 1
(E/Z)-GSK-3β inhibitor 1, 10 mM in DMSO
(E/Z)-GSK-3β inhibitor 1 ，E0381
3-(pyridin-2-ylmethylidene)-1H-indol-2-one
3367-88-2
