TRIS(TRIMETHYLSILYL)PHOSPHITE
- CAS No.
- 1795-31-9
- Chemical Name:
- TRIS(TRIMETHYLSILYL)PHOSPHITE
- Synonyms
- TMSPi;DK604;93412-5ML;Trimethylsilanol phosphite;tritrimethylsilyl phosphite;Tris(trimethylsily)phosphite;ris(trimethylsilyl)phosphite;TRIS(TRIMETHYLSILYL)PHOSPHITE;Tris(trimethylsiloxy)phosphine;Tris(trimethylsilyl)Phosphite>
- CBNumber:
- CB6112770
- Molecular Formula:
- C9H27O3PSi3
- Molecular Weight:
- 298.54
- MDL Number:
- MFCD00015588
- MOL File:
- 1795-31-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Tris(trimethylsilyl) phosphite ≥95.0% (GC) | 93412 | 5ml | $235 |
| Tris(trimethylsilyl) phosphite ≥95.0% (GC) | 93412 | 25ml | $646 |
| Tris(trimethylsilyl) Phosphite >95.0%(NMR) | P1217 | 5mL | $62 |
| Tris(trimethylsilyl) Phosphite | P1217 | 100ML | $732 |
| Tris(trimethylsilyl) Phosphite >95.0%(NMR) | P1217 | 25mL | $247 |
| More product size | |||
| Boiling point | 78-81 °C/8 mmHg (lit.) |
|---|---|
| Density | 0.893 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | RT, stored under nitrogen |
| form | Liquid |
| Specific Gravity | 0.893 |
| color | Clear colorless |
| Water Solubility | Sparingly soluble in water. |
| Sensitive | Air & Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 2043814 |
| InChI | InChI=1S/C9H27O3PSi3/c1-14(2,3)10-13(11-15(4,5)6)12-16(7,8)9/h1-9H3 |
| InChIKey | VMZOBROUFBEGAR-UHFFFAOYSA-N |
| SMILES | [Si](C)(C)(OP(O[Si](C)(C)C)O[Si](C)(C)C)C |
| CAS DataBase Reference | 1795-31-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | 1760 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| TSCA | No | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29319000 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
TRIS(TRIMETHYLSILYL)PHOSPHITE price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93412 | Tris(trimethylsilyl) phosphite ≥95.0% (GC) | 1795-31-9 | 5ml | $235 | 2026-04-30 | Buy |
| Sigma-Aldrich | 93412 | Tris(trimethylsilyl) phosphite ≥95.0% (GC) | 1795-31-9 | 25ml | $646 | 2026-04-30 | Buy |
| TCI Chemical | P1217 | Tris(trimethylsilyl) Phosphite >95.0%(NMR) | 1795-31-9 | 5mL | $62 | 2026-04-30 | Buy |
| TCI Chemical | P1217 | Tris(trimethylsilyl) Phosphite | 1795-31-9 | 100ML | $732 | 2026-04-30 | Buy |
| TCI Chemical | P1217 | Tris(trimethylsilyl) Phosphite >95.0%(NMR) | 1795-31-9 | 25mL | $247 | 2026-04-30 | Buy |
TRIS(TRIMETHYLSILYL)PHOSPHITE Chemical Properties,Uses,Production
Uses
Tris(trimethylsilyl) Phosphite is used in the studies of bisphosphonic acids as effective inhibitor of glutamine synthetase, a promising approach for the discovery of novel drugs against tuberculosis. It also acts as a reagent in the preparation of substituted calix[4]arenes bearing one or two α-hydroxymethylphosphonic acid fragments at upper rim of macrocycle as inhibitors of glutathione S-transferase in vitro.
Preparation
By silylation of anhydrous phosphorous acid (dried by repeated azeotropic evaporation of a solution in THF with dry benzene) with excess Chlorotrimethylsilane and excess Triethylamine in dimethoxyethane, toluene, or Et2O-THF, followed by evaporation of the solvent and vacuum distillation of the residue. The residue, which contains a mixture of tris(trimethylsilyl) phosphite and bis(trimethylsilyl) phosphonate [HP(O)(OTMS)2], can also be heated with sodium (140 °C, 13-22 h), followed by vacuum distillation to obtain pure tris(trimethylsilyl) phosphite.
storage
Extremely hygroscopic; use in a fume hood.
TRIS(TRIMETHYLSILYL)PHOSPHITE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5745 | 58 |
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1008 | 58 |
View Lastest Price from TRIS(TRIMETHYLSILYL)PHOSPHITE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-24 | Tris(trimethylsilyl) Phosphite
1795-31-9
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-04-17 | Tris(trimethylsilyl) Phosphite
1795-31-9
|
$1.10-9.90 | 1kg | 99%min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
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2025-06-20 | TRIS(TRIMETHYLSILYL)PHOSPHITE
1795-31-9
|
$1.00-10.00 | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-

- Tris(trimethylsilyl) Phosphite
1795-31-9
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Tris(trimethylsilyl) Phosphite
1795-31-9
- $1.10-9.90
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- TRIS(TRIMETHYLSILYL)PHOSPHITE
1795-31-9
- $1.00-10.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.







