ChemicalBook >> CAS DataBase List >>TRIS(TRIMETHYLSILYL)PHOSPHITE

TRIS(TRIMETHYLSILYL)PHOSPHITE

CAS No.
1795-31-9
Chemical Name:
TRIS(TRIMETHYLSILYL)PHOSPHITE
Synonyms
TMSPi;DK604;93412-5ML;Trimethylsilanol phosphite;tritrimethylsilyl phosphite;Tris(trimethylsily)phosphite;ris(trimethylsilyl)phosphite;TRIS(TRIMETHYLSILYL)PHOSPHITE;Tris(trimethylsiloxy)phosphine;Tris(trimethylsilyl)Phosphite>
CBNumber:
CB6112770
Molecular Formula:
C9H27O3PSi3
Molecular Weight:
298.54
MDL Number:
MFCD00015588
MOL File:
1795-31-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:26:11
Product description Number Pack Size Price
Tris(trimethylsilyl) phosphite ≥95.0% (GC) 93412 5ml $235
Tris(trimethylsilyl) phosphite ≥95.0% (GC) 93412 25ml $646
Tris(trimethylsilyl) Phosphite >95.0%(NMR) P1217 5mL $62
Tris(trimethylsilyl) Phosphite P1217 100ML $732
Tris(trimethylsilyl) Phosphite >95.0%(NMR) P1217 25mL $247
More product size

TRIS(TRIMETHYLSILYL)PHOSPHITE Properties

Boiling point 78-81 °C/8 mmHg (lit.)
Density 0.893 g/mL at 25 °C (lit.)
refractive index n20/D 1.409(lit.)
Flash point >230 °F
storage temp. RT, stored under nitrogen
form Liquid
Specific Gravity 0.893
color Clear colorless
Water Solubility Sparingly soluble in water.
Sensitive Air & Moisture Sensitive
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
BRN 2043814
InChI InChI=1S/C9H27O3PSi3/c1-14(2,3)10-13(11-15(4,5)6)12-16(7,8)9/h1-9H3
InChIKey VMZOBROUFBEGAR-UHFFFAOYSA-N
SMILES [Si](C)(C)(OP(O[Si](C)(C)C)O[Si](C)(C)C)C
CAS DataBase Reference 1795-31-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-36
RIDADR  1760
WGK Germany  3
10-21
TSCA  No
HazardClass  8
PackingGroup  III
HS Code  29319000
REACH Registrations Active
NFPA 704
2
2 1

TRIS(TRIMETHYLSILYL)PHOSPHITE price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 93412 Tris(trimethylsilyl) phosphite ≥95.0% (GC) 1795-31-9 5ml $235 2026-04-30 Buy
Sigma-Aldrich 93412 Tris(trimethylsilyl) phosphite ≥95.0% (GC) 1795-31-9 25ml $646 2026-04-30 Buy
TCI Chemical P1217 Tris(trimethylsilyl) Phosphite >95.0%(NMR) 1795-31-9 5mL $62 2026-04-30 Buy
TCI Chemical P1217 Tris(trimethylsilyl) Phosphite 1795-31-9 100ML $732 2026-04-30 Buy
TCI Chemical P1217 Tris(trimethylsilyl) Phosphite >95.0%(NMR) 1795-31-9 25mL $247 2026-04-30 Buy
Product number Packaging Price Buy
93412 5ml $235 Buy
93412 25ml $646 Buy
P1217 5mL $62 Buy
P1217 100ML $732 Buy
P1217 25mL $247 Buy

TRIS(TRIMETHYLSILYL)PHOSPHITE Chemical Properties,Uses,Production

Uses

Tris(trimethylsilyl) Phosphite is used in the studies of bisphosphonic acids as effective inhibitor of glutamine synthetase, a promising approach for the discovery of novel drugs against tuberculosis. It also acts as a reagent in the preparation of substituted calix[4]arenes bearing one or two α-hydroxymethylphosphonic acid fragments at upper rim of macrocycle as inhibitors of glutathione S-transferase in vitro.

Preparation

By silylation of anhydrous phosphorous acid (dried by repeated azeotropic evaporation of a solution in  THF with dry benzene) with excess Chlorotrimethylsilane and excess Triethylamine in dimethoxyethane, toluene, or Et2O-THF, followed by evaporation of the solvent and vacuum distillation of the residue. The residue, which contains a mixture of  tris(trimethylsilyl) phosphite and bis(trimethylsilyl) phosphonate [HP(O)(OTMS)2], can also be heated with sodium (140 °C,  13-22 h), followed by vacuum distillation to obtain pure tris(trimethylsilyl) phosphite.

storage

Extremely hygroscopic; use in a fume hood.

14468-90-7
1795-31-9
Synthesis of TRIS(TRIMETHYLSILYL)PHOSPHITE from 1-TRIMETHYLSILYL-2-PYRROLIDINONE

TRIS(TRIMETHYLSILYL)PHOSPHITE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 192)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16512 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 14014 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21586 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Win-Win Chemical CO., Limited
0086-577-64498589 sales@win-winchemical.com CHINA 998 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19936 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5745 58
Jinan Qinmu Fine Chemical Co.,Ltd.
+8618660799346 sales@qinmuchem.com China 1008 58

View Lastest Price from TRIS(TRIMETHYLSILYL)PHOSPHITE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tris(trimethylsilyl) Phosphite pictures 2026-06-24 Tris(trimethylsilyl) Phosphite
1795-31-9
1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Tris(trimethylsilyl) Phosphite pictures 2026-04-17 Tris(trimethylsilyl) Phosphite
1795-31-9
$1.10-9.90 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
TRIS(TRIMETHYLSILYL)PHOSPHITE pictures 2025-06-20 TRIS(TRIMETHYLSILYL)PHOSPHITE
1795-31-9
$1.00-10.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
Phosphorous acid, tristrimethylsilyl Tris(trimethylsily)phosphite TRIS(TRIMETHYLSILYL)PHOSPHITE PHOSPHOROUS ACID TRIS(TRIMETHYLSILYL) ESTER Phosphorousacidtrimethylsilylester TRIS(TRIMETHYLSILYL) PHOSPHITE 95% TRIS(TRIMETHYLSILYL)PHOSPHITE 97+% Phosphorous acid tri(trimethylsilyl) ester Tris(trimethylsiloxy)phosphine Tris(trimethylsilyl) phosphite >=95.0% (GC) Trimethylsilanol phosphite Silanol,1,1,1-trimethyl-,1,1',1''-phosphite Tris(trimethylsilyl)Phosphite> ris(trimethylsilyl)phosphite Triphosphite (trimethylsilica) vinegar Tri (trimethylsilicon) phosphite ester DK604 Tris(trimethylsilyl) phosphite (TMSPi) tritrimethylsilyl phosphite 93412-5ML tri(trimethylsiliconalkaneoxy)phosphino TMSPi 1795-31-9 C9H27O3PSi CH33SiO3P C9H27O4PSi C9H27O3P C9H27O3PSi3 Building Blocks Organic Building Blocks Organic Phosphates/Phosphites Phosphorus Compounds Si-O Compounds Si (Classes of Silicon Compounds) Silicon Compounds (for Synthesis) Silyl Esters Si (Classes of Silicon Compounds) Silicon Compounds (for Synthesis) Silyl Esters Si-O Compounds Synthetic Organic Chemistry