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ChemicalBook >> CAS DataBase List >>1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Structure
1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- structure
CAS No.
129075-56-5
Chemical Name:
1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-
Synonyms
Pd 128763;5-methyl-3,4-dihydroisoquinoline-1-one;3,4-Dihydro-5-methoxyisoquinolin-1(2H)one;3,4-dihydro-5-methyl-1(2H)-isoquinolinone;1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-;5-Methyl-1,2,3,4-tetrahydroisoquinolin-1-one
CBNumber:
CB61237386
Molecular Formula:
C10H11NO
Molecular Weight:
161.2
MDL Number:
MFCD00890474
MOL File:
129075-56-5.mol
MSDS File:
SDS
Last updated:2026-07-14 16:49:18
Product description Number Pack Size Price
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one EFA07556 1g $295
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one EFA07556 10g $1534
PD128763 ≥90% CS-W022412 100mg $17
PD128763 ≥90% CS-W022412 250mg $33
PD128763 ≥90% CS-W022412 1g $98
Request For Quotation

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Properties

Boiling point 413.8±45.0 °C(Predicted)
Density 1.111
storage temp. Sealed in dry,Room Temperature
pka 15.12±0.20(Predicted)
EWG's Food Scores 1
FDA UNII FI8AN8XP0W

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth EFA07556 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one 129075-56-5 1g $295 2026-06-04 Buy
Biosynth EFA07556 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one 129075-56-5 10g $1534 2026-06-04 Buy
ChemScene CS-W022412 PD128763 ≥90% 129075-56-5 100mg $17 2026-06-04 Buy
ChemScene CS-W022412 PD128763 ≥90% 129075-56-5 250mg $33 2026-06-04 Buy
ChemScene CS-W022412 PD128763 ≥90% 129075-56-5 1g $98 2026-06-04 Buy
Product number Packaging Price Buy
EFA07556 1g $295 Buy
EFA07556 10g $1534 Buy
CS-W022412 100mg $17 Buy
CS-W022412 250mg $33 Buy
CS-W022412 1g $98 Buy

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Chemical Properties,Uses,Production

Definition

ChEBI: 3,4-dihydro-5-methylisoquinolinone is a member of isoquinolines.

Synthesis

4-METHYL-1-INDANONE

24644-78-8

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-

129075-56-5

General procedure for the synthesis of 5-methyl-3,4-dihydroisoquinolin-1-one from 4-methyl-2,3-dihydro-1H-inden-1-one: 4.7 g (32.2 mmol) of 2,3-dihydro-4-methyl-1H-inden-1-one was mixed with 53 g of trichloroacetic acid and heated to 65°C. To the reaction mixture was added 4.2 g (64.4 mmol) of azide Sodium azide was added to the reaction mixture and the reaction was kept at 65°C for 18 hours. Subsequently, 1.0 g of sodium azide was added and heating was continued for 4 hours. After completion of the reaction, the mixture was diluted with 200 ml of ice water and extracted with ether. The ether extract was washed sequentially with water and saturated sodium bicarbonate solution, dried over anhydrous magnesium sulfate and concentrated. The residue was purified by silica gel column chromatography (eluent: ether to ether/methanol 95/5). The resulting product was recrystallized from toluene to give 2.45 g (47% yield) of the target compound with a melting point of 141°C-143°C.

References

[1] Patent: US5177075, 1993, A

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Preparation Products And Raw materials

Raw materials

4-METHYL-1-INDANONE Methanol Trichloroacetic acid

Preparation Products

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Suppliers

Global( 47)Suppliers
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CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
career henan chemical co 		+86-0371-86658258 factory@coreychem.com China 29780 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
GIHI CHEMICALS CO.,LIMITED 		+86-571-86217390; +8618058761490 info@gihichemicals.com China 49859 58
Aladdin Scientific 		tp@aladdinsci.com United States 50108 58
TargetMol Chemicals Inc. 		13564774135 marketing@targetmol.com United States 19950 58
Zjartspharm Co., Ltd 		15068876005 jocelynpan@zjarts.com China 9957 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Cuisen Pharmaceutical Technology Co., Ltd. 13472757003 yongnan.wang@cendrix.cn China 970 65
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 		58
Zjartspharm Co., Ltd 		58
Amadis Chemical Company Limited 		58
Adamas Reagent, Ltd. 59
Shanghai Cuisen Pharmaceutical Technology Co., Ltd. 65

View Lastest Price from 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD-128763 pictures 2026-07-14 PD-128763
129075-56-5
 $29.00 10g TargetMol Chemicals Inc.
1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- pictures 2020-01-13 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-
129075-56-5
 $5.00 1KG 98% 100KG Career Henan Chemical Co
  • PD-128763 pictures
  • PD-128763
    129075-56-5
  • $29.00
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129075-56-5(1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-)Related Search:

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1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- 3,4-dihydro-5-methyl-1(2H)-isoquinolinone 3,4-Dihydro-5-methoxyisoquinolin-1(2H)one Pd 128763 5-Methyl-1,2,3,4-tetrahydroisoquinolin-1-one 5-methyl-3,4-dihydroisoquinoline-1-one 129075-56-5