Triethyl 2-phosphonobutyrate
- CAS No.
- 17145-91-4
- Chemical Name:
- Triethyl 2-phosphonobutyrate
- Synonyms
- Ethyl 2-(diethoxyphosphoryl)butanoate;Butanoic acid, 2-(diethoxyphosphinyl)-, ethyl ester;NSC 22423;Triethyl 2-phosphonobutyrate;TRIETHYL-2-PHOSPHONOBUTANOATE;Triethyl 2-phosphonobutyrate,98%;Triethyl alpha-phosphonobutyrate;Triethyl 2-phosphonobutyrate 98%;Triethyle2-phosphonobutyrate, 98%;Ethyl 2-(diethylphosphono)butyrate
- CBNumber:
- CB6127879
- Molecular Formula:
- C10H21O5P
- Molecular Weight:
- 252.24
- MDL Number:
- MFCD00041347
- MOL File:
- 17145-91-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 152-154 °C14 mm Hg(lit.) |
|---|---|
| Density | 1.064 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid |
| Specific Gravity | 1.064 |
| color | Clear colorless |
| Water Solubility | Not miscible or difficult to mix with water. |
| BRN | 1789280 |
| InChI | InChI=1S/C10H21O5P/c1-5-9(10(11)13-6-2)16(12,14-7-3)15-8-4/h9H,5-8H2,1-4H3 |
| InChIKey | GYUCVQSNZFRDRL-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C(P(OCC)(OCC)=O)CC |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29310099 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Triethyl 2-phosphonobutyrate price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 417467 | Triethyl 2-phosphonobutyrate 98% | 17145-91-4 | 5ml | $57.1 | 2023-06-20 | Buy |
| ChemScene | CS-0148079 | Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% | 17145-91-4 | 10g | $34 | 2026-06-04 | Buy |
| ChemScene | CS-0148079 | Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% | 17145-91-4 | 25g | $80 | 2026-06-04 | Buy |
| ChemScene | CS-0148079 | Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% | 17145-91-4 | 50g | $159 | 2026-06-04 | Buy |
| ChemScene | CS-0148079 | Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% | 17145-91-4 | 100g | $208 | 2026-06-04 | Buy |
Triethyl 2-phosphonobutyrate Chemical Properties, Uses, Production
Chemical Properties
clear colorless liquid
Uses
Reactant for preparation of:
- Furospinosulin-1 and analogs as hypoxia-selective antitumor agents
- Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer′s drugs
- Phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents
- PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists
- Notch-sparing γ-secretase inhibitors derived from PPAR agonist library
- Plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis
- Quinone/naphthoquinone-substituted propenoic acids as inhibitors of cell growth and redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor 1 (Ape1/Ref-1)
- α-alkenyl cyclic ethers by asymmetric dehydrative cyclization of ω-hydroxy allyl alcohols catalyzed by Ru complexes of axially chiral naphthylpyridinecarboxylates
- Branched phosphonoethoxyethyl purines as new acyclic nucleoside phosphonates which inhibit Plasmodium falciparum (malarial parasite) hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT)
- Phenylpropanoic acid-type peroxisome proliferator-activated receptor pan agonists as candidate drugs for treatment of altered metabolic homeostasis
Uses
Reactant used for preparation of furospinosulin-1 and analogs as hypoxia-selective antitumor agents, Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimers drugs, phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents, PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists, notch-sparing γ-secretase inhibitors derived from PPAR agonist library and plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis.
reaction suitability
reaction type: C-C Bond Formation
Triethyl 2-phosphonobutyrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Z IntellecChem& Tech. Co., Ltd | 0511-15050866711; 15050866711 | contact@zintellec.com | China | 93 | 62 |
| BeiJing Greenchem Technology Co.,Ltd. | 131-21959385 18804271668 | chemrocking@bjgreenchem.com | China | 272 | 58 |
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from Triethyl 2-phosphonobutyrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | TRIETHYL 2-PHOSPHONOBUTYRATE
17145-91-4
|
$6.00-8.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
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2026-06-30 | Triethyl 2-phosphonobutyrate
17145-91-4
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
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2024-08-05 | TRIETHYL 2-PHOSPHONOBUTYRATE
17145-91-4
|
1kg | 99% | 20MT | Shanghai Bojing Chemical Co.,Ltd. |
-

- TRIETHYL 2-PHOSPHONOBUTYRATE
17145-91-4
- $6.00-8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- Triethyl 2-phosphonobutyrate
17145-91-4
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- TRIETHYL 2-PHOSPHONOBUTYRATE
17145-91-4
- 99%
- Shanghai Bojing Chemical Co.,Ltd.
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