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Triethyl 2-phosphonobutyrate

CAS No.
17145-91-4
Chemical Name:
Triethyl 2-phosphonobutyrate
Synonyms
Ethyl 2-(diethoxyphosphoryl)butanoate;Butanoic acid, 2-(diethoxyphosphinyl)-, ethyl ester;NSC 22423;Triethyl 2-phosphonobutyrate;TRIETHYL-2-PHOSPHONOBUTANOATE;Triethyl 2-phosphonobutyrate,98%;Triethyl alpha-phosphonobutyrate;Triethyl 2-phosphonobutyrate 98%;Triethyle2-phosphonobutyrate, 98%;Ethyl 2-(diethylphosphono)butyrate
CBNumber:
CB6127879
Molecular Formula:
C10H21O5P
Molecular Weight:
252.24
MDL Number:
MFCD00041347
MOL File:
17145-91-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:48

Triethyl 2-phosphonobutyrate Properties

Boiling point 152-154 °C14 mm Hg(lit.)
Density 1.064 g/mL at 25 °C(lit.)
refractive index n20/D 1.432(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
Specific Gravity 1.064
color Clear colorless
Water Solubility Not miscible or difficult to mix with water.
BRN 1789280
InChI InChI=1S/C10H21O5P/c1-5-9(10(11)13-6-2)16(12,14-7-3)15-8-4/h9H,5-8H2,1-4H3
InChIKey GYUCVQSNZFRDRL-UHFFFAOYSA-N
SMILES C(OCC)(=O)C(P(OCC)(OCC)=O)CC
UNSPSC Code 12352108
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29310099
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

Triethyl 2-phosphonobutyrate price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 417467 Triethyl 2-phosphonobutyrate 98% 17145-91-4 5ml $57.1 2023-06-20 Buy
ChemScene CS-0148079 Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% 17145-91-4 10g $34 2026-06-04 Buy
ChemScene CS-0148079 Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% 17145-91-4 25g $80 2026-06-04 Buy
ChemScene CS-0148079 Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% 17145-91-4 50g $159 2026-06-04 Buy
ChemScene CS-0148079 Ethyl 2-(diethoxyphosphoryl)butanoate ≥97% 17145-91-4 100g $208 2026-06-04 Buy
Product number Packaging Price Buy
417467 5ml $57.1 Buy
CS-0148079 10g $34 Buy
CS-0148079 25g $80 Buy
CS-0148079 50g $159 Buy
CS-0148079 100g $208 Buy

Triethyl 2-phosphonobutyrate Chemical Properties, Uses, Production

Chemical Properties

clear colorless liquid

Uses

Reactant for preparation of:

  • Furospinosulin-1 and analogs as hypoxia-selective antitumor agents
  • Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer′s drugs
  • Phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents
  • PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists
  • Notch-sparing γ-secretase inhibitors derived from PPAR agonist library
  • Plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis
  • Quinone/naphthoquinone-substituted propenoic acids as inhibitors of cell growth and redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor 1 (Ape1/Ref-1)
  • α-alkenyl cyclic ethers by asymmetric dehydrative cyclization of ω-hydroxy allyl alcohols catalyzed by Ru complexes of axially chiral naphthylpyridinecarboxylates
  • Branched phosphonoethoxyethyl purines as new acyclic nucleoside phosphonates which inhibit Plasmodium falciparum (malarial parasite) hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT)
  • Phenylpropanoic acid-type peroxisome proliferator-activated receptor pan agonists as candidate drugs for treatment of altered metabolic homeostasis

Uses

Reactant used for preparation of furospinosulin-1 and analogs as hypoxia-selective antitumor agents, Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimers drugs, phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents, PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists, notch-sparing γ-secretase inhibitors derived from PPAR agonist library and plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis.

reaction suitability

reaction type: C-C Bond Formation

Triethyl 2-phosphonobutyrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 138)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Z IntellecChem& Tech. Co., Ltd 0511-15050866711; 15050866711 contact@zintellec.com China 93 62
BeiJing Greenchem Technology Co.,Ltd. 131-21959385 18804271668 chemrocking@bjgreenchem.com China 272 58
Creasyn Finechem(Tianjin) Co., Ltd. 022-83946278 13820372920 sales@creasyn.com China 968 68
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64

View Latest Price from Triethyl 2-phosphonobutyrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TRIETHYL 2-PHOSPHONOBUTYRATE pictures 2026-09-02 TRIETHYL 2-PHOSPHONOBUTYRATE
17145-91-4
$6.00-8.00 1kg 99% Henan Fengda Chemical Co., Ltd
Triethyl 2-phosphonobutyrate pictures 2026-06-30 Triethyl 2-phosphonobutyrate
17145-91-4
1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
TRIETHYL 2-PHOSPHONOBUTYRATE pictures 2024-08-05 TRIETHYL 2-PHOSPHONOBUTYRATE
17145-91-4
1kg 99% 20MT Shanghai Bojing Chemical Co.,Ltd.
2-PHOSPHONOBUTYRIC ACID TRIETHYL ESTER Diethyl 1-(ethoxycarbonyl)propanephosphonate~2-Phosphonobutyric acid triethyl ester diethyl 1-(ethoxycarbonyl)propanephosphonate Diethyl[1-(ethoxycarbonyl)propyl]phosphonate, 98 % alpha-Diethylphosphonobutanoic acid ethyl ester Ethyl 2-(diethoxyphosphinyl)butanoate Ethyl 2-(diethylphosphono)butyrate NSC 22423 Triethyl alpha-phosphonobutyrate Triethyl 2-phosphonobutyrate,98% α-Diethylphosphonobutanoic acid ethyl ester Triethyl 2-phosphonobutyrate 98% Triethyle2-phosphonobutyrate, 98% TRIETHYL-2-PHOSPHONOBUTANOATE DIETHYL[1-(ETHOXYCARBONYL)PROPYL]PHOSPHONATE Butanoic acid, 2-(diethoxyphosphinyl)-, ethyl ester 2-(DIETHOXY-PHOSPHORYL)-BUTYRIC ACID ETHYL ESTER Ethyl 2-(diethoxyphosphoryl)butanoate Triethyl 2-phosphonobutyrate 17145-91-4 17146-91-4 C2H5O2POCHC2H5CO2C2H5 C-C Bond Formation Synthetic Reagents Olefination Horner-Wadsworth-Emmons Reagents C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination