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ICI D1542

CAS No.
147332-48-7
Chemical Name:
ICI D1542
Synonyms
D1542;D 1542;ZD 1542;ICI D1542;Ici D1542,Ici D-1542;4-Hexenoic acid, 6-[(2S,4S,5R)-2-[1-methyl-1-(4-methyl-2-nitrophenoxy)ethyl]-4-(3-pyridinyl)-1,3-dioxan-5-yl]-, (4Z)-
CBNumber:
CB61355529
Molecular Formula:
C25H30N2O7
Molecular Weight:
470.51
MDL Number:
MOL File:
147332-48-7.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:18

ICI D1542 Properties

Boiling point 661.1±50.0 °C(Predicted)
Density 1.225±0.06 g/cm3(Predicted)
pka 4.59±0.10(Predicted)

ICI D1542 Chemical Properties, Uses, Production

Description

Ici D1542 is also known as ZD1542, Ici D1542 is a potent thromboxane A2 synthase inhibitor and receptor antagonist in vitro. ZD1542 is a drug that exhibits both potent,selective TXS inhibition and TXA2 receptor antagonism.

Uses

ICI D1542 is a selective and potent inhibitor of thromboxane A2 (TXA2) synthase and the thromboxane A2 receptor (TP-receptor). ICI D1542 is effective at preventing thrombus formation by redirection of arachidonic acid metabolism[1].

References

[1] S J McAuliffe, et al. Redirection of arachidonic acid metabolism by ICI D1542: effects on thrombus formation in the coronary artery of the anaesthetized dog. r J Pharmacol. 1993 Apr;108(4):901-6. DOI:10.1111/j.1476-5381.1993.tb13484.x

ICI D1542 Preparation Products And Raw materials

Raw materials

Preparation Products

ICI D1542 Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58

147332-48-7 (ICI D1542) Related Search:

ICI D1542 D 1542 D1542 ZD 1542 Ici D1542,Ici D-1542 4-Hexenoic acid, 6-[(2S,4S,5R)-2-[1-methyl-1-(4-methyl-2-nitrophenoxy)ethyl]-4-(3-pyridinyl)-1,3-dioxan-5-yl]-, (4Z)- 147332-48-7