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LAH-1

CAS No.
3018150-68-7
Chemical Name:
LAH-1
Synonyms
LAH-1;3-Pyridazinecarboxamide, N-[3-fluoro-4-[[2-[[(3-hydroxy-1-azetidinyl)carbonyl]amino]-4-pyridinyl]oxy]phenyl]-1-(4-fluorophenyl)-1,6-dihydro-4-methyl-6-oxo-
CBNumber:
CB613900504
Molecular Formula:
C27H22F2N6O5
Molecular Weight:
548.5
MDL Number:
MOL File:
3018150-68-7.mol
Last updated:2025-04-18 09:51:17

LAH-1 Properties

Density 1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 9.00±0.70(predicted)

LAH-1 Chemical Properties, Uses, Production

Uses

LAH-1 is a c-Met inhibitor with oral activity and membrane permeability with an IC50 of 49 nM. LAH-1 has anticancer activity and can induce apoptosis, migration, and invasion[1].

References

[1] Sima L,et al. Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer[J]. Journal of Enzyme Inhibition and Medicinal Chemistry, 2024, 39(1): 2286435. DOI:10.1080/14756366.2023.2286435

LAH-1 Preparation Products And Raw materials

Raw materials

Preparation Products

LAH-1 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
LAH-1 3-Pyridazinecarboxamide, N-[3-fluoro-4-[[2-[[(3-hydroxy-1-azetidinyl)carbonyl]amino]-4-pyridinyl]oxy]phenyl]-1-(4-fluorophenyl)-1,6-dihydro-4-methyl-6-oxo- 3018150-68-7