3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid
- CAS No.
- 155701-61-4
- Chemical Name:
- 3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid
- Synonyms
- DPC974;DPC 974;GW-5638;DPC-974;Etacstil;3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid;2-Propenoic acid, 3-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenyl]-, (2E)-
- CBNumber:
- CB61399675
- Molecular Formula:
- C25H22O2
- Molecular Weight:
- 354.44
- MDL Number:
- MOL File:
- 155701-61-4.mol
- MSDS File:
- SDS
| Boiling point | 508.2±29.0 °C(Predicted) |
|---|---|
| Density | 1.139±0.06 g/cm3(Predicted) |
| pka | 4.53±0.10(Predicted) |
| FDA UNII | WEM4BUT8FL |
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Chemical Properties, Uses, Production
Uses
Etacstil (GW5638) is a estrogen receptor antagonist that displays minimal uterotropic activity in ovariectomized rats and inhibits the agonist activity of Estradiol (HY-B0141), Tamoxifen (HY-13757A) and Raloxifene (HY-13738) in the environment. Etacstil is promising for research of breast cancer and bone protection[1].
References
[1] Willson TM, et al. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology. 1997 Sep;138(9):3901-11. DOI:10.1210/endo.138.9.5358
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
