3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid

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3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Basic information
Product Name:3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid
Synonyms:3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid;GW-5638;2-Propenoic acid, 3-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenyl]-, (2E)-;DPC 974;DPC974;DPC-974;Etacstil
CAS:155701-61-4
MF:C25H22O2
MW:354.44
EINECS:
Product Categories:
Mol File:155701-61-4.mol
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Structure
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Chemical Properties
Boiling point 508.2±29.0 °C(Predicted)
density 1.139±0.06 g/cm3(Predicted)
pka4.53±0.10(Predicted)
Safety Information
MSDS Information
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Usage And Synthesis
UsesEtacstil (GW5638) is a estrogen receptor antagonist that displays minimal uterotropic activity in ovariectomized rats and inhibits the agonist activity of Estradiol (HY-B0141), Tamoxifen (HY-13757A) and Raloxifene (HY-13738) in the environment. Etacstil is promising for research of breast cancer and bone protection[1].
References[1] Willson TM, et al. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology. 1997 Sep;138(9):3901-11. DOI:10.1210/endo.138.9.5358
3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid Preparation Products And Raw materials
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