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PCSK9-IN-20

PCSK9-IN-20 structure

CAS No.: 2929219-77-0

Chemical Name:: PCSK9-IN-20

Synonyms: PCSK9-IN-20;1-Piperazinecarboxylic acid, 4-[[2-[[4-[[(2-cyanoethyl)amino]sulfonyl]benzoyl]amino]-6-benzothiazolyl]methyl]-, 1,1-dimethylethyl ester

CBNumber:: CB614284432

Molecular Formula:: C27H32N6O5S2

Molecular Weight:: 584.71

MDL Number:

MOL File:: 2929219-77-0.mol

Last updated:2025-05-22 08:02:39

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PCSK9-IN-20 Properties

Density	1.370±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	8.274±0.70(predicted)

PCSK9-IN-20 Chemical Properties, Uses, Production

Uses

PCSK9-IN-20 (Compound 3i) is a PCSK9 inhibitor with an IC50 of 3.96 μM. PCSK9-IN-20 decreases PCSK9 and increases LDLR protein expression in vitro[1].

References

[1] Zhixin Ma, et al. Identification of benzothiazoles as novel PCSK9 inhibitors. Bioorg Med Chem Lett. 2023 Nov 6:129542. DOI:10.1016/j.bmcl.2023.129542

PCSK9-IN-20 Preparation Products And Raw materials

Raw materials

Preparation Products

PCSK9-IN-20 Suppliers

Global Suppliers ( 2)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2996	55
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai Beckham Medical Technology Co., Ltd	55
TargetMol Chemicals Inc.	58

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PCSK9-IN-20 1-Piperazinecarboxylic acid, 4-[[2-[[4-[[(2-cyanoethyl)amino]sulfonyl]benzoyl]amino]-6-benzothiazolyl]methyl]-, 1,1-dimethylethyl ester 2929219-77-0