PCSK9-IN-20

PCSK9-IN-20 Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
PCSK9-IN-20 Basic information
Product Name:PCSK9-IN-20
Synonyms:PCSK9-IN-20;1-Piperazinecarboxylic acid, 4-[[2-[[4-[[(2-cyanoethyl)amino]sulfonyl]benzoyl]amino]-6-benzothiazolyl]methyl]-, 1,1-dimethylethyl ester
CAS:2929219-77-0
MF:C27H32N6O5S2
MW:584.71
EINECS:
Product Categories:
Mol File:2929219-77-0.mol
PCSK9-IN-20 Structure
PCSK9-IN-20 Chemical Properties
density 1.370±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka8.274±0.70(predicted)
Safety Information
MSDS Information
PCSK9-IN-20 Usage And Synthesis
UsesPCSK9-IN-20 (Compound 3i) is a PCSK9 inhibitor with an IC50 of 3.96 μM. PCSK9-IN-20 decreases PCSK9 and increases LDLR protein expression in vitro[1].
References[1] Zhixin Ma, et al. Identification of benzothiazoles as novel PCSK9 inhibitors. Bioorg Med Chem Lett. 2023 Nov 6:129542. DOI:10.1016/j.bmcl.2023.129542
PCSK9-IN-20 Preparation Products And Raw materials
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