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STING agonist-23

STING agonist-23 structure

CAS No.: 2361570-16-1

Chemical Name:: STING agonist-23

Synonyms: STING agonist-23;3H-Imidazo[4,5-b]pyridine-6-carboxamide, 3-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-

CBNumber:: CB614292491

Molecular Formula:: C33H35N13O4

Molecular Weight:: 677.72

MDL Number:

MOL File:: 2361570-16-1.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:18

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STING agonist-23 Properties

Density	1.518±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	9.616±0.50(predicted)
form	Solid
color	White to light yellow

STING agonist-23 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0655144	STING agonist-23 99.33%	2361570-16-1	5mg	$460	2026-06-04	Buy
ChemScene	CS-0655144	STING agonist-23 99.33%	2361570-16-1	10mg	$737	2026-06-04	Buy
ChemScene	CS-0655144	STING agonist-23 99.33%	2361570-16-1	25mg	$1473	2026-06-04	Buy
ChemScene	CS-0655144	STING agonist-23 99.33%	2361570-16-1	50mg	$2210	2026-06-04	Buy
ChemScene	CS-0655144	STING agonist-23 99.33%	2361570-16-1	100mg	$3315	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0655144	5mg	$460	Buy
CS-0655144	10mg	$737	Buy
CS-0655144	25mg	$1473	Buy
CS-0655144	50mg	$2210	Buy
CS-0655144	100mg	$3315	Buy

STING agonist-23 Chemical Properties, Uses, Production

Uses

STING agonist-23 (CF502) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains[1].

in vivo

STING agonist-23 adjuvant (20μg STING agonist-23 and 5 μg RBD-Fc per mouse; im; 3 times at 14-day intervals) induces strong antibody immune response induced by the SARS-CoV-2 RBD-Fc protein in mice model^[1].

References

[1] Liu Z, et al. A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs. Cell Res. 2022 Mar;32(3):269-287. DOI:10.1038/s41422-022-00612-2

STING agonist-23 Preparation Products And Raw materials

Raw materials

Preparation Products

STING agonist-23 Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou Younan Technology Co., Ltd	020-82000279 18988941452	YN_research@163.com	China	2984	58
Zhejiang Huida Biotech Co., Ltd.	0571-89903022 18679456698	zilong@hizyme.com	China	7853	58

Supplier	Advantage
Guangzhou Younan Technology Co., Ltd	58
Zhejiang Huida Biotech Co., Ltd.	58

2361570-16-1 (STING agonist-23) Related Search:

1H-Benzimidazole-5-carboxamide, 2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1-[(2S)-2-hydroxy-2-phenylethyl]- NA 3-[(2E)-4-[5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide STING agonist-29 3-[(2E)-4-[5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(1-piperazinyl)propoxy]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide

STING agonist-25

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STING agonist-23 3H-Imidazo[4,5-b]pyridine-6-carboxamide, 3-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]- 2361570-16-1