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Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-

Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- structure

CAS No.: 3039853-91-0

Chemical Name:: Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-

Synonyms: GPR17 modulator-1;Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-

CBNumber:: CB614376306

Molecular Formula:: C15H12ClF3N4O4S

Molecular Weight:: 436.79

MDL Number:

MOL File:: 3039853-91-0.mol

Last updated:2025-04-17 18:22:24

Request For Quotation

Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Properties

Density	1.65±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	-6.39±0.40(predicted)

Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Chemical Properties, Uses, Production

Uses

GPR17 modulator-1 (Compound 2-046) is a modulator for G protein-coupled receptor 17 GPR17, with an IC50<10 nM for hGPR17 in CHO. GPR17 modulator-1 exhibits moderate pharmacokinetic characteristics in mice. GPR17 modulator-1 ix blood-brain barrier (BBB) permeable[1].

References

[1] Han X, et al., Gpr17 modulators and uses thereof. WO2024104462.

Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- GPR17 modulator-1 3039853-91-0